This is an application for a 5-year renewal of an institutional training grant in the Epidemiology and Biostatistics of Aging, funded by NIA since 1996. This multidisciplinary program's goals are to train outstanding predoctoral and postdoctoral candidates to lead the next generation of quantitative research scientists addressing the health of our aging population. This program is conducted jointly by epidemiologists and biostatisticians with a strong commitment to bringing together students in both disciplines to develop expertise in the content areas and methodologies that are essential to advancement of the field. Students are trained to conduct leading- edge research that can inform the development of prevention programs to compress morbidity in the aging population. The program is based in the Departments of Epidemiology and Biostatistics but involves faculty from departments throughout our Schools of Public Health, Medicine, and Nursing. A Program Director in Biostatistics, Co-Director from Epidemiology, 6 other Associate Directors, and 28 other core faculty members will serve as mentors for the trainees. A core curriculum is expected of predoctoral trainees and customized to postdoctoral trainees. Trainees, half each from Epidemiology and Biostatistics, participate in biweekly research in progress meetings, seminars on aging, practica specific to this program, and training to build skills in multidisciplinary collaboration. Research experiences and mentors are selected to ensure high quality research worthy of peer-reviewed publication. We will continue to train students in epidemiologic and biostatistical method and their application to aging, with emphases on the epidemiology of chronic disease, disability and frailty, biostatistics and genetics research methods for gerontology, and the psychosocial epidemiology of late life, and, expand training on the design and conduct of clinical trials and add new emphases in comparative effectiveness and community-based participatory research. Trainees have been highly productive, gained substantial recognition for their research, and launched their careers in appealing positions with emphases on aging. Graduates will be effective leaders of multidisciplinary research teams tackling the health problems associated with the aging US population.

Public Health Relevance

This program addresses a critical need of the field of gerontology for scholars who combine quantitative expertise with immersion in science on aging. Such scholars are crucial because cutting-edge research on aging involves complex data on persons'biological and clinical characteristics, physical and social environments, and health care utilization. Only with such scholars'leadership can data be collected and analyzed so as to yield valid scientific discoveries on improved outcomes for our older population.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZAG1-ZIJ-3 (J2))
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Patmios, Georgeanne E
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Johns Hopkins University
Biostatistics & Other Math Sci
Schools of Public Health
United States
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Wanigatunga, Amal A; Gresham, Gillian K; Kuo, Pei-Lun et al. (2018) Contrasting characteristics of daily physical activity in older adults by cancer history. Cancer 124:4692-4699
Colantuoni, Elizabeth; Scharfstein, Daniel O; Wang, Chenguang et al. (2018) Statistical methods to compare functional outcomes in randomized controlled trials with high mortality. BMJ 360:j5748
Varma, Vijay R; Dey, Debangan; Leroux, Andrew et al. (2018) Total volume of physical activity: TAC, TLAC or TAC(?). Prev Med 106:233-235
Urbanek, Jacek K; Spira, Adam P; Di, Junrui et al. (2018) Epidemiology of objectively measured bedtime and chronotype in US adolescents and adults: NHANES 2003-2006. Chronobiol Int 35:416-434
Wanigatunga, Amal A; Simonsick, Eleanor M; Zipunnikov, Vadim et al. (2018) Perceived Fatigability and Objective Physical Activity in Mid- to Late-Life. J Gerontol A Biol Sci Med Sci 73:630-635
Leroux, Andrew; Xiao, Luo; Crainiceanu, Ciprian et al. (2018) Dynamic prediction in functional concurrent regression with an application to child growth. Stat Med 37:1376-1388
Kheirkhahan, Matin; Chakraborty, Avirup; Wanigatunga, Amal A et al. (2018) Wrist accelerometer shape feature derivation methods for assessing activities of daily living. BMC Med Inform Decis Mak 18:124
Fruiht, Veronica; Chan, Thomas (2018) Naturally Occurring Mentorship in a National Sample of First-Generation College Goers: A Promising Portal for Academic and Developmental Success. Am J Community Psychol 61:386-397
Armstrong, Nicole M; Gitlin, Laura N; Parisi, Jeanine M et al. (2018) Association of physical functioning of persons with dementia with caregiver burden and depression in dementia caregivers: an integrative data analysis. Aging Ment Health :1-8
Miloyan, Beyon; Joseph Bienvenu, O; Brilot, Ben et al. (2018) Adverse life events and the onset of anxiety disorders. Psychiatry Res 259:488-492

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