The purpose of the Integrated Immunology Training Program (IITP) at the University of Texas Southwestern Medical Center (UT Southwestern) is to provide comprehensive training for graduate students, medical scientist trainees, and post-doctoral fellows for cutting-edge immunology-related research careers. The goal is to prepare exceptionally qualified individuals for the investigation and resolution of such significant immune-related problems as autoimmune diseases, allergies, infectious diseases, and immunodeficiencies. These goals will be achieved by a combination of rigorous and intellectually challenging didactic immunology courses, cutting-edge research projects, research presentations, a qualifying exam, seminars, journal clubs, and career development programs. The training program includes the selection IITP faculty who are distributed among thirteen, distinct departments and/or centers (Immunology, Microbiology, Pathology, Cancer Immunobiology, Internal Medicine-Rheumatology, Internal Medicine-Infectious Diseases, Biochemistry, Molecular Biology, Pediatrics, Neurology, Nephrology, Dermatology, Ophthalmology). These faculty are selected based on their leadership role in either a) developing new immunology courses and/or curriculums, b) directing an immunology course, and c) strong commitment in training students and post- doctoral fellows. The IITP is supported by 11 administrative committees that function as part of the program in immunology. Advanced training in immunology is essential for responding to global issues of re-emerging infectious diseases, an aging population suffering the ills of autoimmune diseases, and the recent unfortunate international threat of bioterrorism. The strong didactic courses offered by the Immunology Program provide in-depth coverage of these issues. The research tracts of the IITP faculty are responding to these global challenges. These goals continue to be achieved, as evidenced by the previous trainees that have completed the training and have continued in academia and industry.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI005284-35
Application #
8320939
Study Section
Allergy & Clinical Immunology-1 (AITC)
Program Officer
Prograis, Lawrence J
Project Start
1980-07-01
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2014-08-31
Support Year
35
Fiscal Year
2012
Total Cost
$361,775
Indirect Cost
$27,673
Name
University of Texas Sw Medical Center Dallas
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Chen, Ding; Ireland, Sara J; Remington, Gina et al. (2016) CD40-Mediated NF-κB Activation in B Cells Is Increased in Multiple Sclerosis and Modulated by Therapeutics. J Immunol 197:4257-4265
Estrada, Leonardo D; Ağaç, Didem; Farrar, J David (2016) Sympathetic neural signaling via the β2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8(+) T-cell effector function. Eur J Immunol 46:1948-58
Pendse, Mihir; Hooper, Lora V (2016) Immunology: Mum's microbes boost baby's immunity. Nature 533:42-3
Starokadomskyy, Petro; Gemelli, Terry; Rios, Jonathan J et al. (2016) DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol 17:495-504
Nair, Vidhya R; Franco, Luis H; Zacharia, Vineetha M et al. (2016) Microfold Cells Actively Translocate Mycobacterium tuberculosis to Initiate Infection. Cell Rep 16:1253-8
Scharn, Caitlyn R; Collins, Angela C; Nair, Vidhya R et al. (2016) Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection. J Immunol 196:4641-9
Orme, Jacob J; Du, Yong; Vanarsa, Kamala et al. (2016) Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE. Clin Immunol 169:58-68
Sun, Jing; Li, Ning; Oh, Kyu-Seon et al. (2016) Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use. Sci Signal 9:ra3
Pokatayev, Vladislav; Hasin, Naushaba; Chon, Hyongi et al. (2016) RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice. J Exp Med 213:329-36
Case, Allison; Desmond, Angela; Lopes, Daniel et al. (2016) The Immunogenicity of Peptoid-Protein Conjugates. J Vaccines Vaccin 7:

Showing the most recent 10 out of 83 publications