In the United States, an estimated 20 million people acquire a sexually transmitted disease (STD) each year, leading to $16 billion in health care costs. Globally, 35 million people live with HIV infection, including 1.1 million in the US. The classical STDs and HIV infection share modes of transmission, and consequently, opportunities for prevention. Thus, integrating research and training in STDs and HIV is logical and strategically appropriate. At the University of North Carolina at Chapel Hill (UNC), interdisciplinary training in STDs and HIV is conducted through the Training Program in Sexually Transmitted Diseases (STD) and HIV, currently in its 38th year of support from NIH. Of the living trainees since 1990, 91% of predoctoral and 83% of postdoctoral trainees remain engaged in research, education, or public health activities. In the ongoing cycle of support, we have trained 17 predoctoral and 13 postdoctoral trainees, including four African Americans and two Latinos/Hispanics. Among those that have completed training in the ongoing cycle, all are actively engaged in research or public health activities. The training program supports 6 predoctoral and 4 postdoctoral (MD or PhD) trainees. Predoctoral trainees supported by three academic departments (Microbiology & Immunology, Epidemiology, and Health Behavior); postdoctoral trainees are also supported in the Division of Infectious Diseases. The training faculty comprises 30 members in these four academic units, with support from an additional seven clinical and laboratory resource faculty members. Our training program has three primary goals: 1) Train pre- and post-doctoral trainees to conduct outstanding STD/HIV research; 2) Foster the development of the skills necessary to conduct productive interdisciplinary research; 3) Facilitate professional growth and development to ensure academic and research success. Our program incorporates a research project with a primary mentor in one of four core areas: STD/HIV Pathogenesis & Immunology; Clinical Research in STD/HIV; Epidemiology of STD/HIV; and Behavioral Interventions for STD/HIV. Our program focuses on interdisciplinary activities to foster the trainees' potential for impactful research. Oral and written communication is emphasized, with careful attention to communication outside of the trainee's specific content area. All trainees participate in the STD/HIV seminar, which incorporates both substantive content related to STD/HIV and professional development. This renewal significantly expands the focus on professional development to enhance the retention and success of our trainees in STD/HIV research. Training is individualized using individual development plans. The training program includes a robust evaluation plan, incorporating individual review of the trainees and short- and long-term review of the program. Program evaluation will also include an external advisory board of leading STD/HIV researchers. In summary, the trainees in the UNC STD/HIV Training Program are expected to go on to highly successful careers, conducting interdisciplinary research, and shaping the field of STDs and HIV infection.
Sexually transmitted diseases (STD), including HIV infection, cause substantial morbidity and mortality. To reduce the impact of STD, researchers must be able to work in interdisciplinary teams, bridging basic science, clinical medicine, epidemiology, and behavioral science. This training grant provides training to doctoral students and postdoctoral fellows, including physicians, to create a cadre of young scientists with the skills needed to reduce the burden of STD in the US and worldwide.
|Vwalika, Bellington; Stoner, Marie C D; Mwanahamuntu, Mulindi et al. (2017) Maternal and newborn outcomes at a tertiary care hospital in Lusaka, Zambia, 2008-2012. Int J Gynaecol Obstet 136:180-187|
|Hill, Lauren M; Maman, Suzanne; Kilonzo, Mrema Noel et al. (2017) Anxiety and depression strongly associated with sexual risk behaviors among networks of young men in Dar es Salaam, Tanzania. AIDS Care 29:252-258|
|Jensen, Kara; Dela Pena-Ponce, Myra Grace; Piatak Jr, Michael et al. (2017) Balancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine. Clin Vaccine Immunol 24:|
|Mills, Jon C; Harman, Jeffrey S; Cook, Robert L et al. (2017) Comparative effectiveness of dual vs. single-action antidepressants on HIV clinical outcomes in HIV-infected people with depression. AIDS 31:2515-2524|
|Dennis, Ann M; Hué, Stephane; Learner, Emily et al. (2017) Rising prevalence of non-B HIV-1 subtypes in North Carolina and evidence for local onward transmission. Virus Evol 3:vex013|
|Conserve, Donaldson F; Jennings, Larissa; Aguiar, Carolina et al. (2017) Systematic review of mobile health behavioural interventions to improve uptake of HIV testing for vulnerable and key populations. J Telemed Telecare 23:347-359|
|Lancaster, Kathryn E; Lungu, Thandie; Mmodzi, Pearson et al. (2017) The association between substance use and sub-optimal HIV treatment engagement among HIV-infected female sex workers in Lilongwe, Malawi. AIDS Care 29:197-203|
|Turner, Anne-Marie W; Margolis, David M (2017) Chromatin Regulation and the Histone Code in HIV Latency?. Yale J Biol Med 90:229-243|
|Mills, Jon C; Harman, Jeffrey S; Cook, Robert L et al. (2017) Comparative effectiveness of dual-action versus single-action antidepressants for the treatment of depression in people living with HIV/AIDS. J Affect Disord 215:179-186|
|Stoner, Marie C D; Cole, Stephen R; Price, Joan et al. (2017) Timing of initiation of antiretroviral therapy and risk of preterm birth in studies of HIV-infected pregnant women: the role of selection bias. Epidemiology :|
Showing the most recent 10 out of 249 publications