The Division of Allergy and Infectious Diseases at the University of Washington has trained 115 physician-scientists through continuous funding provided by this training grant since its inception in 1976. More than 85% of these trainees remain in research positions. Many have achieved leadership positions such as two that became Deans of Medicine, one that became a Department Chair, 7 that became Division Heads, and 17 others with leadership positions. Trainees that have completed in the past 10 years have had remarkable early success in research careers, including >75% achieving research funding, >50% with K awards, and >90% publishing one or more papers related to their supported research. The continuing objective of the program is to provide post-doctoral training for physician-scientists committed to an academic career in infectious diseases, with particular emphasis on research training. Each trainee selects a mentor for detailed research training in one of six research tracks. All trainees complete a core curriculum consisting of required didactic, research and clinical activities. Many trainees elect to take course work at the University of Washington and an average of two a year seek a MPH or MSc award. The program generally requires three years of training, two of which are supported by this training grant.

Public Health Relevance

Infectious diseases continue to extract a considerable social and financial toll even in developed countries due to factors such as emerging pathogens, AIDS or other immuno-compromising conditions and antimicrobial resistance;in fact, they represent the leading cause of morbidity and mortality worldwide. The training of new scientists-physicians who can elucidate the basic mechanisms of host defense is critical for the formulation of new and improved strategies to diagnose, treat and prevent infectious diseases.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Institutional National Research Service Award (T32)
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Allergy & Clinical Immunology-1 (AITC)
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Robbins, Christiane M
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University of Washington
Internal Medicine/Medicine
Schools of Medicine
United States
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Simmons, Jason D; Stein, Catherine M; Seshadri, Chetan et al. (2018) Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection. Nat Rev Immunol 18:575-589
Goldberg, Drew W; Tenforde, Mark W; Mitchell, Hannah K et al. (2018) Neurological Sequelae of Adult Meningitis in Africa: A Systematic Literature Review. Open Forum Infect Dis 5:ofx246
Hahn, William O; Butler, Noah S; Lindner, Scott E et al. (2018) cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses. JCI Insight 3:
Tenforde, M W; Longley, N; Meya, D B et al. (2018) Poor specificity of urinary cryptococcal antigen testing: Reply to Drain et al. Prevalence of cryptococcal antigenuria at initial HIV diagnosis in KwaZulu-Natal. HIV Med 19:e47-e48
Bajema, Kristina L; Pakzad-Vaezi, Kaivon; Hawn, Thomas et al. (2017) Tuberculous uveitis: association between anti-tuberculous therapy and clinical response in a non-endemic country. J Ophthalmic Inflamm Infect 7:19
Fisher, Cynthia E; Hohl, Tobias M; Fan, Wenhong et al. (2017) Validation of single nucleotide polymorphisms in invasive aspergillosis following hematopoietic cell transplantation. Blood 129:2693-2701
Bajema, Kristina L; Simonson, Paul D; Greninger, Alex L et al. (2017) Acute Liver Failure Due to Echovirus 9 Associated With Persistent B-Cell Depletion From Rituximab. Open Forum Infect Dis 4:ofx174
Heumann, Christine L; Katz, David A; Dombrowski, Julia C et al. (2017) Comparison of In-Person Versus Telephone Interviews for Early Syphilis and Human Immunodeficiency Virus Partner Services in King County, Washington (2010-2014). Sex Transm Dis 44:249-254
Tenforde, Mark W; Yadav, Ashish; Dowdy, David W et al. (2017) Vitamin A and D Deficiencies Associated With Incident Tuberculosis in HIV-Infected Patients Initiating Antiretroviral Therapy in Multinational Case-Cohort Study. J Acquir Immune Defic Syndr 75:e71-e79
Mazengia, E; Kawakami, V; Rietberg, K et al. (2017) Hospital-acquired listeriosis linked to a persistently contaminated milkshake machine. Epidemiol Infect 145:857-863

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