The success of the Baylor College of Medicine (BCM) Training Program for Clinical Research on AIDS (Training Program) can be measured in the outstanding 15 young trainees produced since the last funding cycle in 2002. The Training Program has been particularly successful in recruiting underserved trainees into independent research careers in AIDS. These trainees have performed splendidly in conducting original research, publishing their data in peer-reviewed literature, and preparing for academic, government, or institutional careers in AIDS research. The BCM Training Program has been able to fill all of its trainee slots with the highest caliber postdoctoral applicants, half of who were of minority background or women. For example, of the 15 trainees since 2002, seven were minorities (47%) and eight were women (53%). Six of the 15 trainees (40%) have pursued international AIDS as their primary interest. Eleven of the 15 trainees since 2002 (73%) have selected careers in AIDS or related research at universities, public hospitals serving disadvantaged minority citizens, or government research institutions. We have established international training sites in Bucharest, Romania and Gaborone, Botswana. Bangkok, Thailand is designated as a developing international site. There will be three training tracks in the program: 1) laboratory-based clinical research, 2) clinical research trials, and 3) epidemiology with M.P.H. degree. Domestic and international trainees may participate in any of the 3 tracks. In the first 12 months all trainees must take courses in the BCM Clinical Scientist Training Program, 1-2 courses such as biostatistics, ethics, institutional review board and consent issues, and a clinical research seminar series. There will be a formal review of the program, faculty, and trainees on a 6-month basis. Mentoring committees will assist the mentor in guiding trainees in their independent research projects, including publication of their research work. In summary, the BCM Training Program has been highly successful in preparing outstanding trainees for independent research careers in AIDS in the past and, with continued support, will do so again in the future. Examination of the subsequent careers of the 26 trainees in the BCM Training Program since its beginning in 1992 reveals that the investment in these gifted young people has yielded returns far in excess of the most optimistic expectations.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Acquired Immunodeficiency Syndrome Research Review Committee (AIDS)
Program Officer
Sharma, Opendra K
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Baylor College of Medicine
Schools of Medicine
United States
Zip Code
Wei, Qin; Sha, Youbao; Bhattacharya, Abhisek et al. (2014) Regulation of IL-4 receptor signaling by STUB1 in lung inflammation. Am J Respir Crit Care Med 189:16-29
Buscher, April; Mugavero, Michael; Westfall, Andrew O et al. (2013) The association of clinical follow-up intervals in HIV-infected persons with viral suppression on subsequent viral suppression. AIDS Patient Care STDS 27:459-66
Buscher, April; Latini, David M; Hartman, Christine et al. (2013) Utility of a partner communication scale and a personal meaning scale in newly diagnosed HIV-infected persons. J Assoc Nurses AIDS Care 24:126-34
Ramakrishnan, Rajesh; Rice, Andrew P (2012) Cdk9 T-loop phosphorylation is regulated by the calcium signaling pathway. J Cell Physiol 227:609-17
Ramakrishnan, Rajesh; Donahue, Hart; Garcia, David et al. (2011) Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas. PLoS One 6:e27271
Buscher, April; Hartman, Christine; Kallen, Michael A et al. (2011) Validity of self-report measures in assessing antiretroviral adherence of newly diagnosed, HAART-naive, HIV patients. HIV Clin Trials 12:244-54
Toracchio, Sonia; Foyle, Annette; Sroller, Vojtech et al. (2010) Lymphotropism of Merkel cell polyomavirus infection, Nova Scotia, Canada. Emerg Infect Dis 16:1702-9
Toracchio, Sonia; Kozinetz, Claudia A; Killen, Deanna E et al. (2009) Variable frequency of polyomavirus SV40 and herpesvirus EBV in lymphomas from two different urban population groups in Houston, TX. J Clin Virol 46:154-60
Baliga, Christopher S; van Maanen, Marc; Chastain, Michael et al. (2006) Vaccination of mice with replication-defective human immunodeficiency virus induces cellular and humoral immunity and protects against vaccinia virus-gag challenge. Mol Ther 14:432-41
Giordano, Thomas P; Visnegarwala, Fehmida; White Jr, A Clinton et al. (2005) Patients referred to an urban HIV clinic frequently fail to establish care: factors predicting failure. AIDS Care 17:773-83

Showing the most recent 10 out of 17 publications