The stated objective of the proposed training program is to prepare outstanding individuals for careers in research and teaching in basic mechanisms of AIDS pathogenesis. Training will be directed toward three interrelated basic research areas: (l) molecular virology and pathogenesis of HIV; (2) antiviral drug discovery and design; and (3) mucosal immunology and vaccine development. Prior to admission to the BMAP Training Program, both Ph.D. and M.D./Ph.D. predoctoral trainees will undertake three different laboratory rotations, make brief oral or poster presentations on their research experiences and will attend lectures given through the Center for AIDS Research, the Comprehensive Cancer Center and individual academic departments. Journal club participation is mandatory. Predoctoral trainees will choose a mentor after their first year (Ph.D.) or second year (M.D./Ph.D), and will then fulfill the requirements of their particular department's Ph.D. program during that next year or more. Students who then pass a qualifying examination are allowed to apply for candidacy for the Ph.D. degree and entry into the BMAP training program. Funding for Ph.D. and M.D./Ph.D. students will be covered from other sources until they actually enter the BMAP Training Program. After admission to the BMAP Program, a dissertation committee will monitor the students progress at six months intervals until the Ph.D. degree is awarded. The postdoctoral training program is quite conventional in design and implementation. Each trainee is committed to at least two, and preferably three, years in the program. Ph.D.s will commit 100% time to research, while M.D.s will commit 80%. All trainees will be enrolled in a journal club and will take at least one advanced course decided upon by the trainee, the Program Advisory Committee and the trainee's preceptor. Trainees will be periodically evaluated for continuation in the program during a meeting of the Committee, the trainee and the trainee's preceptor.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007493-05
Application #
2886228
Study Section
Special Emphasis Panel (SRC (61))
Program Officer
Sager, Polly R
Project Start
1995-04-01
Project End
2000-06-30
Budget Start
1999-04-01
Budget End
2000-06-30
Support Year
5
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Brawner, K M; Kumar, R; Serrano, C A et al. (2017) Helicobacter pylori infection is associated with an altered gastric microbiota in children. Mucosal Immunol 10:1169-1177
Robinson, Tanya O; Zhang, Mingce; Ochsenbauer, Christina et al. (2017) CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte derived macrophages. Virology 504:79-87
Gu, Linlin; Krendelchtchikova, Valentina; Krendelchtchikov, Alexandre et al. (2016) Adenoviral vectors elicit humoral immunity against variable loop 2 of clade C HIV-1 gp120 via ""Antigen Capsid-Incorporation"" strategy. Virology 487:75-84
Matthews, Qiana L; Farrow, Anitra L; Rachakonda, Girish et al. (2016) Epitope Capsid-Incorporation: New Effective Approach for Vaccine Development for Chagas Disease. Pathog Immun 1:214-233
Farrow, Anitra L; Peng, Binghao J; Gu, Linlin et al. (2016) A Novel Vaccine Approach for Chagas Disease Using Rare Adenovirus Serotype 48 Vectors. Viruses 8:78
Michel, Katherine G; Huijbregts, Richard P H; Gleason, Jonathan L et al. (2015) Effect of hormonal contraception on the function of plasmacytoid dendritic cells and distribution of immune cell populations in the female reproductive tract. J Acquir Immune Defic Syndr 68:511-8
Gu, Linlin; Farrow, Anitra L; Krendelchtchikov, Alexandre et al. (2015) Utilizing the antigen capsid-incorporation strategy for the development of adenovirus serotype 5-vectored vaccine approaches. J Vis Exp :e52655
Speer, Alexander; Sun, Jim; Danilchanka, Olga et al. (2015) Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages. Mol Microbiol 97:881-97
Jones, Christopher M; Wells, Ryan M; Madduri, Ashoka V R et al. (2014) Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling. Proc Natl Acad Sci U S A 111:1945-50
Brawner, Kyle M; Morrow, Casey D; Smith, Phillip D (2014) Gastric microbiome and gastric cancer. Cancer J 20:211-6

Showing the most recent 10 out of 60 publications