The events of September 11th, the subsequent fatal anthrax attacks, and the epidemic of sever acute respiratory syndrome (SARS) in 2002-3 exemplified the potential for loss of life, major social disruption, and economic losses that can follow the introduction of a transmissible disease in a susceptible population. The identification of cases of H5N1 influenza, both in birds and subsequently in humans underscores the importance of the development of rigorous methods in infectious disease epidemiology, surveillance, monitoring and modeling. Although neither the SARS coronavirus nor H5N1 influenza were deliberately introduced, they share many characteristics of potential bioterrorist agents, and many of the contingency plans developed for dealing with biological attacks received their first tests in the SARS epidemic. The goal of the Harvard School of Public Health's Interdisciplinary Program in Infectious Disease Epidemiology (IPIDE) through this resubmission of our competing continuation is to train 4 pre-doctoral candidates in epidemiologic research methods through two years of formal didactic classroom training at the Harvard School of Public Health, which includes courses from a new concentration in infectious disease epidemiology and biodefense (www.hsDh.harvard.edu/ideDi/) and two years of research under close supervision of our 21 program faculty members, leading to either a DS, or PHD. Given the increase in the courses offered biodefense, students can take a total of 17.5 credits in courses that directly deal with biodefense epidemiology, almost twice the number of credits necessary to allow students to choose biodefense as a concentration within biostatistics epidemiology. Program faculty include internationally recognized investigators in the fields of virology, epidemiology, immunology and biostatistics. Harvard's IPIDE has been running successfully for 10 years, and this training grant has helped develop and launch a new cadre of independent investigators with infectious disease epidemiologic training linking basic and applied research into the detection and prevention of emerging infectious diseases. A cumulative total of 18 students have been supported;nine have graduated;they have published 186 peer-reviewed manuscripts. For the current submission, we are proposing to support 4 pre-doctorial students over the next five year project period.

Public Health Relevance

This training grant supports the training of doctorial students develop rigorous methods in infectious disease epidemiology, surveillance, monitoring and modeling so that they will be able to prevent and detect outbreaks of emerging epidemics.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007535-14
Application #
8272536
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Mcsweegan, Edward
Project Start
1998-09-30
Project End
2014-05-31
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
14
Fiscal Year
2012
Total Cost
$144,796
Indirect Cost
$8,714
Name
Harvard University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115
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Chanda, Michael M; Ortblad, Katrina F; Mwale, Magdalene et al. (2017) Contraceptive use and unplanned pregnancy among female sex workers in Zambia. Contraception 96:196-202
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Chanda, Michael M; Perez-Brumer, Amaya G; Ortblad, Katrina F et al. (2017) Barriers and Facilitators to HIV Testing Among Zambian Female Sex Workers in Three Transit Hubs. AIDS Patient Care STDS 31:290-296
Mayer, Kenneth H; Oldenburg, Catherine E; Novak, David S et al. (2016) Early Adopters: Correlates of HIV Chemoprophylaxis Use in Recent Online Samples of US Men Who Have Sex with Men. AIDS Behav 20:1489-98
Jain, Sachin; Oldenburg, Catherine E; Mimiaga, Matthew J et al. (2016) High Levels of Concomitant Behavioral Health Disorders Among Patients Presenting for HIV Non-occupational Post-exposure Prophylaxis at a Boston Community Health Center Between 1997 and 2013. AIDS Behav 20:1556-63
Geldsetzer, Pascal; Ortblad, Katrina; Bärnighausen, Till (2016) The efficiency of chronic disease care in sub-Saharan Africa. BMC Med 14:127
Kunkel, Amber; Crawford, Forrest W; Shepherd, James et al. (2016) Benefits of continuous isoniazid preventive therapy may outweigh resistance risks in a declining tuberculosis/HIV coepidemic. AIDS 30:2715-2723
Abuelezam, Nadia N; McCormick, Alethea W; Fussell, Thomas et al. (2016) Can the Heterosexual HIV Epidemic be Eliminated in South Africa Using Combination Prevention? A Modeling Analysis. Am J Epidemiol 184:239-48
Kunkel, Amber; Crawford, Forrest W; Shepherd, James et al. (2016) Benefits of continuous isoniazid preventive therapy may outweigh resistance risks in a declining TB/HIV co-epidemic. AIDS :

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