This training program has been designed to provide pre- and postdoctoral candidates with the individual intellectual and technical skills required to become outstanding academic scientists in the field of immunobiology.
The aim i s to utilize the growth of Immunobiology and the expansion of its faculty at Mount Sinai as a resource to create a fertile environment for the growth of graduate students and postdoctoral fellows. Each trainee will be exposed not only to direct laboratory research, but will have the opportunity (actually be required) to participate in the educational programs focused on Immunobiology established here at Mount Sinai. For physician scientists there will be ample opportunity to immerse themselves in translational research programs relating to cytokine biology, HIV related disorders, mucosal immunity, autoimmunity and primary immune deficiency. There is formal course work, seminar series, journal clubs and work in progress meetings (attended by the entire Immunology faculty and trainees). A single faculty member acts as a preceptor for a given fellow or graduate student supervising his/her laboratory work, orchestrating an appropriate training program (e.g. course work), and providing an environment that will help foster maturation towards an independent career in immunology research. The program has successfully recruited outstanding trainees from a number of prestigious institutions who have been attracted to Mount Sinai because of the enormous growth in the basic sciences, excellence in research, a protective and nurturing mentoring environment and a clear commitment to student and post-doctoral fellowship training.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007605-10
Application #
8320924
Study Section
Special Emphasis Panel (ZAI1-QV-I (M2))
Program Officer
Prograis, Lawrence J
Project Start
2001-07-01
Project End
2013-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
10
Fiscal Year
2012
Total Cost
$111,427
Indirect Cost
$10,829
Name
Icahn School of Medicine at Mount Sinai
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
Campisi, L; Cummings, R J; Blander, J Magarian (2014) Death-defining immune responses after apoptosis. Am J Transplant 14:1488-98
Swartz, Talia H; Esposito, Anthony M; Durham, Natasha D et al. (2014) P2X-selective purinergic antagonists are strong inhibitors of HIV-1 fusion during both cell-to-cell and cell-free infection. J Virol 88:11504-15
Cravedi, Paolo; van der Touw, William; Heeger, Peter S (2013) Complement regulation of T-cell alloimmunity. Semin Nephrol 33:565-74
Cravedi, P; Leventhal, J; Lakhani, P et al. (2013) Immune cell-derived C3a and C5a costimulate human T cell alloimmunity. Am J Transplant 13:2530-9
Bonito, Anthony J; Aloman, Costica; Fiel, M Isabel et al. (2013) Medullary thymic epithelial cell depletion leads to autoimmune hepatitis. J Clin Invest 123:3510-24
Kwan, Wing-hong; van der Touw, William; Paz-Artal, Estela et al. (2013) Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells. J Exp Med 210:257-68
Yu, Joyce E; De Ravin, Suk See; Uzel, Gulbu et al. (2011) High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. Clin Immunol 138:14-22
Fernandez-Sesma, Ana; Marukian, Svetlana; Ebersole, Barbara J et al. (2006) Influenza virus evades innate and adaptive immunity via the NS1 protein. J Virol 80:6295-304
Ulane, Christina M; Kentsis, Alex; Cruz, Cristian D et al. (2005) Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain. J Virol 79:10180-9