This is the second competing renewal of a training program to provide high quality pre- and postdoctoral training in Immunology and Molecular Pathogenesis to the most qualified candidates. The faculty in the graduate Program in Immunology and Molecular Pathogenesis (IMP) have the expertise required to provide the foundation that is critical for outstanding predoctoral and postdoctoral training. Many of the participating faculty have extensive training records, in some cases initiated at their former institutions prior to their recruitment to Emory. The areas of research represented by this program have outstanding potential for future investigations and for providing new insights into disease pathogenesis. The research programs of the faculty fall into three main training areas: 1) pathogenesis of infectious diseases;2) molecular virology;and 3) immunobiology. The faculty of IMP are members of six basic science or clinical departments in the School of Medicine, as well as Yerkes National Primate Center, the Biology Department of Emory College, and the U.S. Centers for Disease Control and Prevention (CDC). During the previous ten years of this training program, this grant has provided support for 48 predoctoral and 13 postdoctoral trainees. Two of the postdoctoral trainees are currently independent investigators (LaJolla Institute of Allergy and Immunology;UCSF) and two others have already received individual training awards to complete their postdoctoral work. Of the 48 predoctoral trainees, 27 are still in predoctoral training. Twenty students have received their Ph.D.s of which 1 is an Assistant Professor, 1 is a CDC staff scientist, 15 and are currently postdoctoral fellows. Of these 48 students supported by the training grant only one has left the program (a nearly 100% retention rate), which is better than the IMP program overall. Therefore this training grant has improved immunology and virology training at Emory, supporting not only our most outstanding students and postdocs, but enriching the intellectual environment by funding external speakers in the Program seminar series.
The relevance for this training program includes the importance of interdisciplinary training in providing the foundation for investigating mechanisms of pathogenesis and the extensive previous involvement of the participating faculty in pre- and postdoctoral training. The availability of funds from this training grant has had a profound positive effect on immunology and virology training at Emory University.
|Moniuszko, Marcin; Liyanage, Namal P M; Doster, Melvin N et al. (2015) Glucocorticoid treatment at moderate doses of SIVmac251-infected rhesus macaques decreases the frequency of circulating CD14+CD16++ monocytes but does not alter the tissue virus reservoir. AIDS Res Hum Retroviruses 31:115-26|
|Ferrer, Ivana R; Hester, Joanna; Bushell, Andrew et al. (2014) Induction of transplantation tolerance through regulatory cells: from mice to men. Immunol Rev 258:102-16|
|Chinnadurai, Raghavan; Copland, Ian B; Patel, Seema R et al. (2014) IDO-independent suppression of T cell effector function by IFN-?-licensed human mesenchymal stromal cells. J Immunol 192:1491-501|
|Sakai, Shunsuke; Kauffman, Keith D; Schenkel, Jason M et al. (2014) Cutting edge: control of Mycobacterium tuberculosis infection by a subset of lung parenchyma-homing CD4 T cells. J Immunol 192:2965-9|
|Anderson, Kristin G; Mayer-Barber, Katrin; Sung, Heungsup et al. (2014) Intravascular staining for discrimination of vascular and tissue leukocytes. Nat Protoc 9:209-22|
|Althof, Nadine; Harkins, Stephanie; Kemball, Christopher C et al. (2014) In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease. J Virol 88:5087-99|
|Khan, Abdul Ghafoor; Whidby, Jillian; Miller, Matthew T et al. (2014) Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2. Nature 509:381-4|
|Liyanage, Namal P M; Gordon, Shari N; Doster, Melvin N et al. (2014) Antiretroviral therapy partly reverses the systemic and mucosal distribution of NK cell subsets that is altered by SIVmac??? infection of macaques. Virology 450-451:359-68|
|Lo, Michael K; Bird, Brian H; Chattopadhyay, Anasuya et al. (2014) Single-dose replication-defective VSV-based Nipah virus vaccines provide protection from lethal challenge in Syrian hamsters. Antiviral Res 101:26-9|
|Liu, Baoyu; Chen, Wei; Evavold, Brian D et al. (2014) Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling. Cell 157:357-68|
Showing the most recent 10 out of 34 publications