The goal of the Wisconsin Allergy Research Training (WISCART) program is to provide research training for postdoctoral fellows in Allergy and Immunology to prepare trainees for careers as independent academic research scientists. Objectives to achieve this goal include 1) to establish a high quality and productive research project, 2) to develop a progressive record of publication in respected research journals, 3) to obtain extramural grant funding during the fellowship, and 4) to have a minimum of 50% of the graduates of this program pursue a career in Allergy and Immunology research. There are generally 6-8 Allergy/immunology fellows in the UW program, and 4 fellows supported by the WISCART program. All fellows are MDs who have completed residency training in either Pediatrics or Internal Medicine. The first year of the program is funded by monies provided by the departmental and divisional funds, and is primarily clinical in nature. After the clinical year, the second and third years (2 positions per year), which are research intensive, are funded by WISCART. Additional years of training are encouraged, and are funded by research grants or other sources. The WISCART trainers are a diverse group of clinical, translational and basic scientists, and there are an exceptional number of opportunities for trainee research projects. The curriculum takes advantage of a number of institutional resources, including the University of Wisconsin Institute of Clinical and Translational Research, to provide comprehensive clinical research training, and optional advanced degree programs in clinical research.

Public Health Relevance

(See Instructions): Allergic diseases and asthma are among the most common diseases, and are increasing for reasons that are not well understood. The goal of this program is to provide training in clinical and translational research to physician scientists who wish to pursue careers devoted to research in these critical areas of unmet medical need.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Institutional National Research Service Award (T32)
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Allergy & Clinical Immunology-1 (AITC)
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Prograis, Lawrence J
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University of Wisconsin Madison
Schools of Medicine
United States
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Esquivel, Ann; Busse, William W (2017) Anaphylaxis Conundrum: A Trojan Horse Phenomenon. J Allergy Clin Immunol Pract 5:325-329
Kloepfer, Kirsten M; Sarsani, Vishal K; Poroyko, Valeriy et al. (2017) Community-acquired rhinovirus infection is associated with changes in the airway microbiome. J Allergy Clin Immunol 140:312-315.e8
Bashir, Hiba; Grindle, Kristine; Vrtis, Rose et al. (2017) Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens. J Allergy Clin Immunol :
Ramratnam, Sima K; Visness, Cynthia M; Jaffee, Katy F et al. (2017) Relationships among Maternal Stress and Depression, Type 2 Responses, and Recurrent Wheezing at Age 3 Years in Low-Income Urban Families. Am J Respir Crit Care Med 195:674-681
Branchfield, Kelsey; Nantie, Leah; Verheyden, Jamie M et al. (2016) Pulmonary neuroendocrine cells function as airway sensors to control lung immune response. Science 351:707-10
Sterkel, Alana K; Lorenzini, Jenna L; Fites, J Scott et al. (2016) Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity. Cell Host Microbe 19:361-74
Nantie, Leah; Sun, Xin (2016) An Ephrin-Eph Tug and Push in Left-Right Organ Placement. Dev Cell 39:282-283
Kakumanu, Sujani; Jaffee, Katy; Visness, Cynthia M et al. (2016) The influence of atopy and asthma on immune responses in inner-city adults. Immun Inflamm Dis 4:80-90
Nanjappa, Som Gowda; Hernández-Santos, Nydiaris; Galles, Kevin et al. (2015) Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia. PLoS Pathog 11:e1005161
Bell, Matthew C; Busse, William W (2015) Is It Asthma or Is It COPD: The Overlap Syndrome. J Allergy Clin Immunol Pract 3:641-2; quiz 643

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