The goal of the proposed training program is to continue to provide tailored strong research skills and knowledge in the discipline of Pediatric Infectious Diseases for pediatric investigators for a career in academic pediatrics and research organizations. Our proposed training program is multidisciplinary, combining resources and faculty from multiple departments of the Johns Hopkins University School of Medicine and Bloomberg School of Public Health who share an interest in mentoring and promoting biomedical research to young physician investigators. Postdoctoral fellows are trained predominantly in a single area in either basic or clinical investigation with ample exposure to many disciplines related to Pediatric Infectious Diseases research. Twenty-one training faculty (including the program director), 13 primarily in basic science investigation and eight in clinical investigations have been selected for the strength of their research programs, prior experience in training biomedical scientists and level of their extramural research support. We also included five associate professors and recruited two assistant professors who meet the selection criteria and also possess strong potential as training faculty. Postdoctoral fellowship candidates will have completed a minimum of three years of residency training in Pediatrics. They will be selected based upon their commitment to an academic career and their interest in our Infectious Diseases training program. The trainees' research training (approximately 80% time commitment) is supplemented with progressive training in clinical Pediatric Infectious Diseases, tailored coursework and seminars, participation in clinical and research conferences, training in preparation of manuscripts and grants, biomedical ethics and research presentation skills. The Division of Pediatric Infectious Diseases has had an outstanding track record of producing physician investigators who are committed to careers in academic Pediatric Infectious Diseases and biomedical research. Since the inception of this training grant in 2002, all ten graduates are currently active members of Pediatric Infectious Diseases programs in medical institutions and government settings, and one received the NIH Director's Innovator Award, three became recipients of NIH K08/K23 Award and one received the Thrasher Research Early Career Award. Our program has also been highly successful in recruiting highly competitive applicants from underrepresented minority groups, representing five of the 15 trainees enrolled in the program (including the incoming fellow for the academic year of 2013-2014). Based on our proposed research program, resources, and track record, we request support for 3 postdoctoral training positions.

Public Health Relevance

We propose to provide research training in Pediatric Infectious Diseases and all graduates of our training program will have a significant impact on the Pediatric Infectious Diseases-related research needs and workforce of the nation.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI052071-15
Application #
9280832
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Coomes, Stephanie
Project Start
2002-07-01
Project End
2018-07-31
Budget Start
2017-08-01
Budget End
2018-07-31
Support Year
15
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Li, David X; Sick-Samuels, Anna C; Suwantarat, Nuntra et al. (2018) Risk Factors for Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Carriage Upon Pediatric Intensive Care Unit Admission. Infect Control Hosp Epidemiol 39:116-118
Koay, Wei Li A; Siems, Lilly V; Persaud, Deborah (2018) The microbiome and HIV persistence: implications for viral remission and cure. Curr Opin HIV AIDS 13:61-68
Akinboyo, Ibukunoluwa C; Voskertchian, Annie; Gorfu, Gezahegn et al. (2018) Epidemiology and risk factors for recurrent Staphylococcus aureus colonization following active surveillance and decolonization in the NICU. Infect Control Hosp Epidemiol 39:1334-1339
Salazar-Austin, N; Kulich, M; Chingono, A et al. (2018) Age-Related Differences in Socio-demographic and Behavioral Determinants of HIV Testing and Counseling in HPTN 043/NIMH Project Accept. AIDS Behav 22:569-579
Koay, Wei Li A; Lindsey, Jane C; Uprety, Priyanka et al. (2018) Intestinal Integrity Biomarkers in Early Antiretroviral-Treated Perinatally HIV-1-Infected Infants. J Infect Dis 218:1085-1089
Griffith, David; Snyder, Jeremy; Dell, Shanna et al. (2018) Impact of a youth-focused care model on retention and virologic suppression among young adults with HIV cared for in an adult HIV clinic. J Acquir Immune Defic Syndr :
Tamma, Pranita D; Fan, Yunfan; Bergman, Yehudit et al. (2018) Successful Treatment of Persistent Burkholderia cepacia Complex Bacteremia with Ceftazidime-Avibactam. Antimicrob Agents Chemother 62:
Akinboyo, Ibukunoluwa C; Sick-Samuels, Anna C; Singeltary, Emily et al. (2018) Multistate Outbreak of an Emerging Burkholderia cepacia Complex Strain Associated With Contaminated Oral Liquid Docusate Sodium. Infect Control Hosp Epidemiol 39:237-239
Salazar-Austin, Nicole; Akinboyo, Ibukunoluwa; Jain, Sanjay K (2017) Successful cure of extensively drug-resistant pulmonary tuberculosis in a young child. Lancet Infect Dis 17:898-899
Griffith, David C; Aronis, Konstantinos N; Orozco, Angela M et al. (2017) Premature Coronary Artery Disease and ST-Elevation Myocardial Infarction in a 24-Year-Old Man With Perinatally Acquired Human Immunodeficiency Virus: A Case Report. Open Forum Infect Dis 4:ofw260

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