The primary objective of the Immunology of Infectious Disease (IID) research training program is to train young scientists in cutting edge microbiology and immunology, to learn to connect these two disciplines, and to do research at the interface of classic microbiology and immunology. Solving the problem of infectious disease, which is responsible for overwhelming morbidity and mortality worldwide, requires scientists well versed in both the microbial and host sides of the equations. The IID training program brings together faculty from throughout the University of Pittsburgh, including the School of Medicine, Graduate School of Public Health and the undergraduate Faculty of Arts and Sciences, to train students and post-docs in a variety of approaches to the study of host-pathogen interactions. Microbes from viruses to bacteria to parasites to fungi are represented and immunologic areas including innate immunity, adaptive immunity virulence strategies for immune evasion and vaccine development. Emphasis is placed on the study of emerging diseases, global infectious diseases, and biodefense organisms. Graduate students in the Molecular Virology and Microbiology and the Immunology graduate programs, under the umbrella of the Interdisciplinary Biomedical Graduate Program, performing dissertation research in the lab of an IID faculty member are eligible for support, once they have advanced to candidacy. Post-doctoral fellows in these labs are also eligible for support. Support for 4 pre-doctoral students each for two years, is requested;post-doctoral awards are for one year, with the opportunity for competitive renewal for a second year. Two post-doctoral slots, at a level of 1-3 years post-degree, per year are requested.
Training students and fellows in the immunology of infectious disease provides the next generation of scientists who will develop treatments and vaccines against diseases caused by bacteria, viruses and other microbes. This training program teaches young scientists both microbiology and immunology and provides a framework for research in both disciplines.
|Kleinman, Adam J; Sivanandham, Ranjit; Pandrea, Ivona et al. (2018) Regulatory T Cells As Potential Targets for HIV Cure Research. Front Immunol 9:734|
|Hvorecny, Kelli L; Dolben, Emily; Moreau-Marquis, Sophie et al. (2018) An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung. Am J Physiol Lung Cell Mol Physiol 314:L150-L156|
|Maiello, Pauline; DiFazio, Robert M; Cadena, Anthony M et al. (2018) Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison. Infect Immun 86:|
|Lane, Whitney C; Dunn, Matthew D; Gardner, Christina L et al. (2018) The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent. MBio 9:|
|Weiss, Christopher M; Trobaugh, Derek W; Sun, Chengqun et al. (2018) The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins. mSphere 3:|
|Brown, Judy J; Short, Sarah P; Stencel-Baerenwald, Jennifer et al. (2018) Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection. J Virol 92:|
|Drummond, Coyne G; Bolock, Alexa M; Ma, Congrong et al. (2017) Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner. Proc Natl Acad Sci U S A 114:1672-1677|
|Dembowski, Jill A; Dremel, Sarah E; DeLuca, Neal A (2017) Replication-Coupled Recruitment of Viral and Cellular Factors to Herpes Simplex Virus Type 1 Replication Forks for the Maintenance and Expression of Viral Genomes. PLoS Pathog 13:e1006166|
|Li, Jihong; Freedman, John C; Evans, Daniel R et al. (2017) CodY Promotes Sporulation and Enterotoxin Production by Clostridium perfringens Type A Strain SM101. Infect Immun 85:|
|Corry, Jacqueline; Arora, Nitin; Good, Charles A et al. (2017) Organotypic models of type III interferon-mediated protection from Zika virus infections at the maternal-fetal interface. Proc Natl Acad Sci U S A 114:9433-9438|
Showing the most recent 10 out of 98 publications