The goal of this program is to leverage the clinical and basic research expertise and resources available at Northwestern University to train MD and MD/PhD fellows in infectious disease translational research. This training program will build on the Infectious Diseases Fellowship Program, which attracts top-notch physician-scientists. The clinical expertise of the Infectious Disease Division together with the long-standing basic science strengths in microbiology and immunology at Northwestern University have created a rich environment for translational research. The proposed training program will serve as a nidus of collaboration between these two groups. Each trainee will work with both a primary research mentor and a clinical co-mentor, which will foster interaction between research and clinical faculty and enhance the translational aspects of the fellow's research experience. A training program consisting of a Master's of Science in Clinical Investigation degree, seminars, career development programs, and education in the ethical conduct of research has been developed to promote excellence in research. We propose to fund one highly qualified MD or MD/PhD fellow per year for a two-year intensive research experience. Furthermore, the Northwestern University Department of Medicine has committed to match this award should it be funded, such that resources will be available for a total of two trainees per year to complete two years in the program. Together, these activities will enable trainees to obtain funding and develop into independent researchers.

Public Health Relevance

The continued emergence of new pathogens, the unacceptable morbidity and mortality due to conventional infections, and the epidemics of antibiotic-resistant bacteria highlight the need for well-trained researchers in infectious disease. This postgraduate training program in infectious diseases will provide training for investigators capable of harnessing the discoveries in the basic sciences of microbiology and immunology to develop novel interventions aimed at ameliorating the burden of infectious diseases.

Agency
National Institute of Health (NIH)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI095207-03
Application #
8661108
Study Section
Microbiology and Infectious Diseases Research Committee (MID)
Program Officer
Robbins, Christiane M
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60611
Fitzpatrick, Margaret A; Ozer, Egon; Bolon, Maureen K et al. (2015) Influence of ACB complex genospecies on clinical outcomes in a U.S. hospital with high rates of multidrug resistance. J Infect 70:144-52
Fitzpatrick, Margaret; Zembower, Teresa; Malczynski, Michael et al. (2014) Outcomes of an enhanced surveillance program for carbapenem-resistant Enterobacteriaceae. Infect Control Hosp Epidemiol 35:419-22