The purpose of the training program in dermatology is to provide advanced training in basic science research as it relates to the study of the skin. The program is directed towards the training of physician-scientists for academic careers, but will also include Ph.D.'s committed to dermatology and to the study of skin-related problems. The training faculty group have particular expertise in the study of: 1 ) morphologic and biochemical assessment of cutaneous development and repair; 2) keratinocyte-specific proteins and function, 3 ) extracellular matrix metabolism and, 4) structural proteins of the extracellular matrix including elastin, proteoglycans, and collagens. The areas under investigation in these laboratories utilize a variety of approaches involving cell biology, enzymology, protein chemistry, modern molecular biology, gene transfection, immunology, and cell culture. Specialized training in areas not offered by our the staff will be open to the trainees through the close association with the faculty of other departments in the medical school e.g., Dr. Peter Byers, Professor, Dept. of Pathology, Dr. William Carter, Professor, Dept. of Pathobiology and Fred Hutchinson Cancer Research Center (FHCRC), Karen Stephens, Research Associate Professor, Dept. of Medicine, Division of Medical Genetics, Dr. Curtis Omiecinski, Professor, Dept. of Environmental Health, Dr. Buddy Ratner, Professor Dept. of Chemical Engineering, Dr. Nicole Gibran, Associate Professor, Dept. of Surgery and Dr. Mark Bothwell, Professor, Dept. of Physiology and Biophysics. There are research seminars presented by the division as well as seminars offered in a number of associated basic science departments including Biological Structure. The dermatology training grant program is intended to train individuals with a strong commitment to pursue a full-time academic research career. Continued support is requested for 3 postdoctoral trainees who have received the degree of either M.D. or Ph.D. Candidates are selected from the clinical training program and/or from outside applicants applying directly to the research program. The training program has developed a program for expanding the pool of qualified minority applicants as well as recruiting and retaining those applicants. Likewise, a program is in place for teaching research integrity.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007019-28
Application #
6632558
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Moshell, Alan N
Project Start
1975-07-01
Project End
2006-04-30
Budget Start
2003-05-01
Budget End
2004-04-30
Support Year
28
Fiscal Year
2003
Total Cost
$173,811
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Underwood, Robert A; Usui, Marcia L; Zhao, Ge et al. (2011) Quantifying the effect of pore size and surface treatment on epidermal incorporation into percutaneously implanted sphere-templated porous biomaterials in mice. J Biomed Mater Res A 98:499-508
Chien, Andy J; Moon, Randall T (2007) WNTS and WNT receptors as therapeutic tools and targets in human disease processes. Front Biosci 12:448-57
Wang, Hao; Presland, Richard B; Piepkorn, Michael (2005) A search for CDKN2A/p16INK4a mutations in melanocytic nevi from patients with melanoma and spouse controls by use of laser-captured microdissection. Arch Dermatol 141:177-80
Reichel, Jennifer L; Peirson, Ryan P; Berg, Daniel (2004) Teaching and evaluation of surgical skills in dermatology: results of a survey. Arch Dermatol 140:1365-9
Bub, Jennifer L; Berg, Daniel; Slee, April et al. (2004) Management of lentigo maligna and lentigo maligna melanoma with staged excision: a 5-year follow-up. Arch Dermatol 140:552-8
Dinulos, James G H; Mentele, Laurel; Fredericks, L Page et al. (2003) Keratinocyte expression of human beta defensin 2 following bacterial infection: role in cutaneous host defense. Clin Diagn Lab Immunol 10:161-6
Dank, J P; Kim, S; Parisi, M A et al. (1999) Outcome after surgical repair of junctional epidermolysis bullosa-pyloric atresia syndrome: a report of 3 cases and review of the literature. Arch Dermatol 135:1243-7
Haycox, C L; Leach-Scampavia, D; Olerud, J E et al. (1999) Quantitative detection of silicone in skin by means of electron spectroscopy for chemical analysis (ESCA). J Am Acad Dermatol 40:719-25
Kern, D E; Kidd, P G; Moe, R et al. (1998) Analysis of T-cell receptor gene rearrangement in lymph nodes of patients with mycosis fungoides. Prognostic implications. Arch Dermatol 134:158-64
Zeltinger, J; Holbrook, K A (1997) A model system for long-term serum-free suspension organ culture of human fetal tissues: experiments on digits and skin from multiple body regions. Cell Tissue Res 290:51-60

Showing the most recent 10 out of 22 publications