This program trains physicians and basic scientists for research in rheumatology and contributes to the availability of investigators in rheumatic diseases. Persons with an MD or MD, PhD degree who have completed their training in internal medicine or pediatrics, and persons with a PhD degree will be considered for the program if they have a commitment to an investigative career. Trainees will be provided theoretical and practical experience in biomedical research related to rheumatic diseases. Trainees will participate in seminars, lectures and selected courses to further theoretical knowledge. Trainees with MD degrees will gain expertise in diagnosis and treatment of rheumatic diseases, providing them with teaching abilities in this field and focusing their evolving research expertise on rheumatic diseases. Trainees devote at least 40 hours per week to training in research. Areas of research training will be related to immunobiology, genetics, vascular pathology, clinical epidemiology, or outcomes of rheumatic diseases. Preceptors will be members of the Division of Rheumatology, Immunology-Rheumatology in the Department of Pediatrics, or basic science departments including Immunology, Orthopedics, Genome Sciences and Pathology. The facilities consist of research laboratories of participating faculty members. The outstanding research milieu of the UW is an important factor in overall training. The period of training will be three years. Upon completion of training, career options include academic appointments in schools of medicine for research, or teaching in rheumatology. Six postdoctoral positions are requested, one or two being from Pediatric Rheumatology.

National Institute of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Institutional National Research Service Award (T32)
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Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Mancini, Marie
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University of Washington
Internal Medicine/Medicine
Schools of Medicine
United States
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Gorman, Jacquelyn A; Hundhausen, Christian; Errett, John S et al. (2017) The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity. Nat Immunol 18:744-752
Sontheimer, Clayton; Liggitt, Denny; Elkon, Keith B (2017) Ultraviolet B Irradiation Causes Stimulator of Interferon Genes-Dependent Production of Protective Type I Interferon in Mouse Skin by Recruited Inflammatory Monocytes. Arthritis Rheumatol 69:826-836
Arkatkar, Tanvi; Du, Samuel W; Jacobs, Holly M et al. (2017) B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity. J Exp Med 214:3207-3217
Jackson, Shaun W; Jacobs, Holly M; Arkatkar, Tanvi et al. (2016) B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. J Exp Med 213:733-50
Gazitt, Tal; Lood, Christian; Elkon, Keith B (2016) Citrullination in Rheumatoid Arthritis-A Process Promoted by Neutrophil Lysis? Rambam Maimonides Med J 7:
Buechler, Matthew B; Akilesh, Holly M; Hamerman, Jessica A (2016) Cutting Edge: Direct Sensing of TLR7 Ligands and Type I IFN by the Common Myeloid Progenitor Promotes mTOR/PI3K-Dependent Emergency Myelopoiesis. J Immunol 197:2577-82
Dam, Elizabeth M; Habib, Tania; Chen, Janice et al. (2016) The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans. Clin Immunol 173:171-180
Shenoi, Susan; Bell, Samantha; Wallace, Carol A et al. (2015) Juvenile idiopathic arthritis in relation to maternal prenatal smoking. Arthritis Care Res (Hoboken) 67:725-30
Elkon, Keith B; Sontheimer, Clayton (2014) Editorial: toll-like receptor 7: more than skin deep? Arthritis Rheumatol 66:481-4
Jackson, Shaun W; Scharping, Nicole E; Kolhatkar, Nikita S et al. (2014) Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation. J Immunol 192:4525-32

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