The overall goal of the Academic Rheumatology and Clinical Immunology Training Program at UCSF is to provide advanced researchtraining to qualified individuals with MD, MD/PhD, or PhD degrees who plan to pursue careers in academic rheumatology. This program provides trainees with an environment in which they can learn: (1) the latest scientific advances in their chosen field;(2) state-of-the-art methods;(3) how to investigate a problem in depth;(4) what constitutes good science;and (5) approaches to translating research discoveries into improved recognition and treatment of the rheumatic diseases. This training program takes advantage of the resources of the Rheumatology Divisions at Moffitt-Long University Hospital, San Francisco General Hospital, and the San Francisco VA Medical Center and integrates the UCSF Division of Pediatric Rheumatology to support training in both adult and pediatric rheumatology/immunology. Leadership and faculty of these divisions are committed to provide protected mentoring time and full salary supplementation for trainees. The program also draws upon the strength of the UCSF Immunology Program to provide trainees a broad range of research and training opportunities in a highly collaborative environment. For the current renewal, the program has added new faculty, including the Director of the UCSF CTSA Program. The program and its trainees will thus be in a position to benefit from the diverse opportunities for translational ?esearch training that exist across the UCSF system in addition to those that are already part of this training program. For over two decades, the UCSF Rheumatology and Clinical Immunology Training Program has had particular strength in basic biomedical research, and health services research/outcomes research. More recently, the program has added major new research programs in genetic epidemiology of rheumatic diseases and clinical trials of novel biologic therapies for rheumatic diseases. This breadth of activity creates an outstanding environment for collaboration among faculty and trainees. This training grant supports six lighly qualified trainees through two or three years of rigorous scientific training, with the objective that they will successfully devote their subsequent careers to the study of the rheumatic and immunologic diseases.

Public Health Relevance

(Seeinstructions): This program has a sustained record of success in training young scientists for academic careers in adult and pediatric rheumatology, many of whom have gone on to become leaders in the field. This success is also reflected in the quality of the most recent and current trainees. This program therefore addresses the critical need for the next generation of academic rheumatologists that will be essential for continued nrnnrpss in thp fmht anainst rhpnmatir. anrl immnnnlnnir riispasps in rhilrirpn and adults

National Institute of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Mancini, Marie
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California San Francisco
Internal Medicine/Medicine
Schools of Medicine
San Francisco
United States
Zip Code
Nayak, Renuka R; Turnbaugh, Peter J (2016) Mirror, mirror on the wall: which microbiomes will help heal them all? BMC Med 14:72
Freedman, Tanya S; Tan, Ying X; Skrzypczynska, Katarzyna M et al. (2015) LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife 4:
Richman, Nicole C; Yazdany, Jinoos; Graf, Jonathan et al. (2013) Extraarticular manifestations of rheumatoid arthritis in a multiethnic cohort of predominantly Hispanic and Asian patients. Medicine (Baltimore) 92:92-7
Baker-Lepain, Julie C; Lynch, John A; Parimi, Neeta et al. (2012) Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis. Arthritis Rheum 64:1457-65
Malladi, Arundathi S; Sack, Kenneth E; Shiboski, Stephen C et al. (2012) Primary Sjögren's syndrome as a systemic disease: a study of participants enrolled in an international Sjögren's syndrome registry. Arthritis Care Res (Hoboken) 64:911-8
Lawson, Erica F; Yazdany, Jinoos (2012) Healthcare quality in systemic lupus erythematosus: using Donabedian's conceptual framework to understand what we know. Int J Clin Rheumtol 7:95-107
Baker-LePain, Julie C; Lane, Nancy E (2012) Role of bone architecture and anatomy in osteoarthritis. Bone 51:197-203
Baker-LePain, Julie C; Nakamura, Mary C; Shepherd, John et al. (2011) Assessment of bone remodelling in childhood-onset systemic lupus erythematosus. Rheumatology (Oxford) 50:611-9
Baker-LePain, Julie C; Nakamura, Mary C; Lane, Nancy E (2011) Effects of inflammation on bone: an update. Curr Opin Rheumatol 23:389-95
Baker-LePain, Julie C; Luker, Kali R; Lynch, John A et al. (2011) Active shape modeling of the hip in the prediction of incident hip fracture. J Bone Miner Res 26:468-74

Showing the most recent 10 out of 31 publications