The Dermatology T32 training program at Case Western Reserve University (Case) is based upon a tradition of collaborative multidisciplinary interdepartmental scholarly interactions reflected in both the research and educational aspects of the program. The overall goal of the program is to attract talented individuals, with the potential for success in academic investigative dermatology and cutaneous biology research. The program uniquely serves a considerable talent base which exists in the North/Central Ohio region, with four major clinical dermatology residencies, four skin-oriented research centers;P30 Skin Diseases Research Center (SDRC), Center for Medical Mycology (CMM), the Murdough Family Center for Psoriasis (MFCP), and a psoriasis P50 Center of Research Translation (CORT) together with a rapidly expanding top-tier biomedical research environment in Cleveland, ranked #4 in NIH funding among Dermatology Departments. Because cutaneous biology and dermatology have been a consistent focus of excellence and institutional investment at both Case and University Hospitals Case Medical Center (UHCMC), a unique skin application- oriented training program has been established with scientific disciplines including;Cellular/Molecular Biology, Systems Biology/Bioinformatics, Genetics/Animal Models and Translational Research. Due to Departmental growth, increased basic faculty scientists, and more prominence within the basic research groups at Case via the SDRC, CMM, CORT and MFCP, the Department has been attracting highly qualified graduate students for training and interested medical students performing masters theses. Therefore, we are also seeking two pre-doctoral training positions along with two short term positions to bolster support for interested medical students in addition to two postdoctoral training positions. We feel that this will allow us to enhance our pipeline of training physician scientists, as well as develop Ph.D. scientists with a commitment to cutaneous biology. The duration of the training will be up to two years for postdoctoral (PGY 2) M.D., Ph.D. or M.D., Ph.D. fellows and up to three years for predoctoral graduate students. Short term positions will be offered for the summer months. This T32 strives to meet the pressing need for M.D.'s and Ph.D.'s who are trained in an ethical, collaborative, trans-disciplinary environment and who can apply modern research tools and systems approaches to cutaneous diseases. Researchers with such training are essential for the design, execution, and interpretation of the most promising and innovative projects, which involve complex interactive teams in Medical Schools, Institutes and Industry.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007569-20
Application #
8501373
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Cibotti, Ricardo
Project Start
1991-07-01
Project End
2014-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
20
Fiscal Year
2013
Total Cost
$164,587
Indirect Cost
$15,147
Name
Case Western Reserve University
Department
Dermatology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Conic, Ruzica Z; Arbesman, Joshua (2018) Melanoma Tumor Characteristics: An Analysis of Mutational Burden and Copy Number Alterations by Patient Age and Stage. J Invest Dermatol 138:1218-1221
Tomalka, Amanda G; Resto-Garay, Ivelisse; Campbell, Kerry S et al. (2018) In vitro Evidence That Combination Therapy With CD16-Bearing NK-92 Cells and FDA-Approved Alefacept Can Selectively Target the Latent HIV Reservoir in CD4+ CD2hi Memory T Cells. Front Immunol 9:2552
Rambhia, Pooja H; Honda, Kord; Arbesman, Joshua (2018) Nivolumab induced inflammation of seborrheic keratoses: a novel cutaneous manifestation in a metastatic melanoma patient. Melanoma Res 28:475-477
Rambhia, Pooja H; Conic, Ruzica Z; Murad, Aizuri et al. (2018) Updates in therapeutics for folliculitis decalvans: A systematic review with evidence-based analysis. J Am Acad Dermatol :
de Jesus, Tristan; Shukla, Sudhanshu; Ramakrishnan, Parameswaran (2018) Too sweet to resist: Control of immune cell function by O-GlcNAcylation. Cell Immunol 333:85-92
Conic, Rosalynn R Z; Piliang, Melissa; Bergfeld, Wilma et al. (2018) Vitamin D Status in Scarring and Non-Scarring Alopecia. J Am Acad Dermatol :
Rambhia, Pooja H; Conic, Ruzica Z; Atanaskova-Mesinkovska, Natasha et al. (2018) Role of graft-versus-host disease in the development of secondary skin cancers in hematopoietic stem cell transplant recipients: A meta-analysis. J Am Acad Dermatol 79:378-380.e3
Scott, Jeffrey F; Conic, Ruzica Z; Thompson, Cheryl L et al. (2018) Stage IV melanoma of unknown primary: A population-based study in the United States from 1973 to 2014. J Am Acad Dermatol 79:258-265.e4
Conic, Ruzica Z; Ko, Jennifer; Allam, Sherihan H et al. (2018) Mixed Versus Pure Variants of Desmoplastic Melanoma: The Cleveland Clinic Experience. Ann Plast Surg 80:277-281
Santus, Pierachille; Rizzi, Maurizio; Radovanovic, Dejan et al. (2018) Psoriasis and Respiratory Comorbidities: The Added Value of Fraction of Exhaled Nitric Oxide as a New Method to Detect, Evaluate, and Monitor Psoriatic Systemic Involvement and Therapeutic Efficacy. Biomed Res Int 2018:3140682

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