This is a competitive renewal of the rheumatology training program at Boston University School of Medicine. It experienced an unfortunate transition in the past cycle with the death of the PI, Dr. Joseph Kornin March 2005 after a long illness. Dr. David Felson, the prior Associate Director, assumed leadership of the grant after Dr. Korn's demise. Under Dr. Felson's leadership and the active involvement of faculty in rheumatology and other departments, the training program is vibrant, growing and actively training rheumatologists and others to enter academic careers in both clinical and bench laboratory research. All of those funded by this T32 in last 3-4 years have entered academic medicine, and most of them, in addition to or after their T32 support, have successfully competed for funding for their own career development grants. Even others in this training program not supported by the T32 have evidenced academic success with high rates of funding and other milestones of academic success. We have trained MD and PhD postdoctoral trainees, although most have been MD's. Given the small size of the rheumatology fellowship program (2 MD fellows per year all of whom are recruited with a research focus), we are not requesting an expansion of the postdoctoral training opportunities, in part to limit T32 trainees to our most competitive. There is a prominent clinical research component to this training grant with at least half of fellows pursuing clinical research track that includes taking courses toward a degree in our School of Public Health and participation in our K30program (CREST program). Among unique elements of our training program are the recent inclusions of doctoral trained physical therapists as postdoctoral clinical research trainees. We hope to continue to train a few physical therapists especially in the clinical research track. Also, we take advantage of the breadth of bench laboratory experience and excellence at Boston University to permit our trainees interested in a bench to train with outstanding scientists doing work of relevance to rheumatic diseases.

National Institute of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Institutional National Research Service Award (T32)
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Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Mao, Su-Yau
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Boston University
Internal Medicine/Medicine
Schools of Medicine
United States
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Lenna, Stefania; Han, Rong; Trojanowska, Maria (2014) Endoplasmic reticulum stress and endothelial dysfunction. IUBMB Life 66:530-7
White, Daniel K; Tudor-Locke, Catrine; Zhang, Yuqing et al. (2014) Daily walking and the risk of incident functional limitation in knee osteoarthritis: an observational study. Arthritis Care Res (Hoboken) 66:1328-36
White, Daniel K; Tudor-Locke, Catrine; Felson, David T et al. (2013) Do radiographic disease and pain account for why people with or at high risk of knee osteoarthritis do not meet physical activity guidelines? Arthritis Rheum 65:139-47
Stefanik, J J; Niu, J; Gross, K D et al. (2013) Using magnetic resonance imaging to determine the compartmental prevalence of knee joint structural damage. Osteoarthritis Cartilage 21:695-9
Grayson, Peter C; Cuthbertson, David; Carette, Simon et al. (2013) New features of disease after diagnosis in 6 forms of systemic vasculitis. J Rheumatol 40:1905-12
Dubreuil, Maureen; Neogi, Tuhina; Chen, Clara A et al. (2013) Increased risk of recurrent gout attacks with hospitalization. Am J Med 126:1138-41.e1
Grayson, Peter C; Tomasson, Gunnar; Cuthbertson, David et al. (2012) Association of vascular physical examination findings and arteriographic lesions in large vessel vasculitis. J Rheumatol 39:303-9
Grayson, Peter C; Maksimowicz-McKinnon, Kathleen; Clark, Tiffany M et al. (2012) Distribution of arterial lesions in Takayasu's arteritis and giant cell arteritis. Ann Rheum Dis 71:1329-34
Stefanik, Joshua J; Roemer, Frank W; Zumwalt, Ann C et al. (2012) Association between measures of trochlear morphology and structural features of patellofemoral joint osteoarthritis on MRI: the MOST study. J Orthop Res 30:1-8
Grayson, Peter C; Kim, Seo Young; LaValley, Michael et al. (2011) Hyperuricemia and incident hypertension: a systematic review and meta-analysis. Arthritis Care Res (Hoboken) 63:102-10

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