A long term goal of the Department of Dermatology at the University of Wisconsin- Madison is to produce scientific leaders for our discipline. To accomplish this goal, we propose to establish a Training Program for individualized career-building for post-doctoral candidates who have a definite commitment to an academic career in cutaneous biology. An aggressive plan to recruit MDs who have shown a clear commitment to academic dermatology will be implemented. The Program is led by an established investigator who was a successful director for more than ten years on a T32 in cutaneous biology at another institution. Integral to the Program is a selection process that emphasizes on quality of previous research experience and potential for independent investigation. This program rests on a foundation of well-funded research in the biology of skin diseases that includes 13 investigators and $14 million of annual direct cost from the National Institutes of Health, Department of Defense and Veterans Affairs. Six trainers are within the Department of Dermatology and seven others are established mentors from other departments with strong training records and research programs emphasizing skin biology. Many have collaborative relationships with each other and with faculty across the University. Participating faculty employ state of the art technology to study some of the most complex problems in investigative dermatology at the mechanistic level. Each trainee will be guided to apply for mentored individual NRSA or K awards. Formal training will also be provided in the ethical conduct of being a scientist and critical analysis of data for publication of results. In addition, all trainees will participate in courses, workshops, symposia and data presentation exercises. To develop communication skills, trainees will be required to present their work once a month at work in progress sessions which are held where six PI's of the Department and all fellows (over 40 at this time) are present and at the annual meeting of the Society for Investigative Dermatology and/or other national meetings. In summary, the goal of this program is to capitalize on the strengths of the funded investigators in the Department of Dermatology, as well as the University, to provide experience that is likely to lead to a productive and independent career in investigative dermatology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR055893-05
Application #
8461168
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Baker, Carl
Project Start
2009-05-01
Project End
2014-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
5
Fiscal Year
2013
Total Cost
$220,580
Indirect Cost
$18,300
Name
University of Wisconsin Madison
Department
Dermatology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Goldminz, Ari M; Suárez-Fariñas, Mayte; Wang, Andrew C et al. (2015) CCL20 and IL22 Messenger RNA Expression After Adalimumab vs Methotrexate Treatment of Psoriasis: A Randomized Clinical Trial. JAMA Dermatol 151:837-46
Wu, Jianqiang; Salva, Katrin A; Wood, Gary S (2015) c-CBL E3 ubiquitin ligase is overexpressed in cutaneous T-cell lymphoma: its inhibition promotes activation-induced cell death. J Invest Dermatol 135:861-868
Chamcheu, Jean Christopher; Pal, Harish C; Siddiqui, Imtiaz A et al. (2015) Prodifferentiation, anti-inflammatory and antiproliferative effects of delphinidin, a dietary anthocyanidin, in a full-thickness three-dimensional reconstituted human skin model of psoriasis. Skin Pharmacol Physiol 28:177-88
Spurgeon, Megan E; Cheng, Jingwei; Bronson, Roderick T et al. (2015) Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice. Cancer Res 75:1068-79
Salva, Katrin A; Bennett, Daniel; Longley, Jack et al. (2015) Multispectral Imaging Approach to the Diagnosis of a CD20+ Cutaneous T-cell Lymphoproliferative Disorder: A Case Report. Am J Dermatopathol 37:e116-21
Salva, Katrin Agnes; Wood, Gary S (2015) Epigenetically Enhanced Photodynamic Therapy (ePDT) is Superior to Conventional Photodynamic Therapy for Inducing Apoptosis in Cutaneous T-Cell Lymphoma. Photochem Photobiol 91:1444-51
Salva, Katrin A; Haemel, Anna K; Pincus, Laura B et al. (2014) Expression of CD31/PECAM-1 (platelet endothelial cell adhesion molecule 1) by blastic plasmacytoid dendritic cell neoplasms. JAMA Dermatol 150:73-6
Gandhi, Mitul D; Evens, Andrew M; Fenske, Timothy S et al. (2014) Pancreatitis in patients treated with brentuximab vedotin: a previously unrecognized serious adverse event. Blood 123:2895-7
Salva, Katrin A; Stenstrom, Melissa; Breadon, Jonith Y et al. (2014) Possible association of cutaneous Rosai-Dorfman disease and chronic Crohn disease: a case series report. JAMA Dermatol 150:177-81
Pei, Qinglin; Zuleger, Cindy L; Macklin, Michael D et al. (2014) A conditional predictive p-value to compare a multinomial with an overdispersed multinomial in the analysis of T-cell populations. Biostatistics 15:129-39

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