The inter-disciplinary ?Training Program in Cancer Research? at Fox Chase Cancer Center, currently in its 40th year, focuses on preparing a cadre of outstanding cancer scientists through rigorous research and impactful, targeted mentoring. Continued funds are requested to support 10 postdoctoral trainees. The highly collaborative participating faculty consist of 50 Cancer Center members of the Fox Chase Cancer Center and Temple Health. Collectively, these faculty possess interests that span the cancer spectrum, including cell growth control, signal transduction, inflammation, epigenetics, cancer prevention, bio-behavioral cancer research, and developmental therapeutics. The postdoctoral pool is extremely strong; there is an average of 3-4 applicants per open slot, and the majority of applicants received graduate training at outstanding institutions, and published in high-impact journals. The program offers diverse training in areas relevant to cancer research, with a combination of didactic and laboratory-based training, including seminar series and journal clubs, scientific writing courses, career development seminars, and individualized development plans. Input from the postdoctoral pool is extensive and highly valued in shaping this program; trainee satisfaction is best exemplified by our long-standing placement in the Top 20 ?Best Places in the United States for Postdoctoral Training?, as published in The Scientist magazine (through 2012). Trainee slots are highly competitive, all slots have been continuously filled for the last 3 funding cycles, and >75% of trainees who have completed training report that they are still doing research directly relevant to cancer. Appointments are made for one year, with an option to renew for a second year of support. A chief objective of our Research Training Plan is to equip our trainees with the skills needed to transition to impactful careers in cancer biology and medicine, recognizing that fundamental contributions to the cancer effort can be achieved in a wide array of career paths. In summary, this proposal continues a long history of excellence in training in cancer biology at Fox Chase.

Public Health Relevance

This grant application seeks funds to support the training of postdoctoral fellows in the fields of cancer biology, prevention, and control. Fox Chase Cancer Center is a national leader in the study and treatment of cancer, and we have a long-standing and successful track record of training highly productive postdoctoral fellows who dedicate their professional careers to cancer research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
2T32CA009035-41
Application #
9208938
Study Section
Subcommittee F - Institutional Training and Education (NCI-F)
Program Officer
Lim, Susan E
Project Start
1975-07-01
Project End
2021-08-31
Budget Start
2016-09-15
Budget End
2017-08-31
Support Year
41
Fiscal Year
2016
Total Cost
$539,790
Indirect Cost
$39,984
Name
Research Institute of Fox Chase Cancer Center
Department
Type
DUNS #
064367329
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Arora, Sanjeevani; Huwe, Peter J; Sikder, Rahmat et al. (2017) Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods. Cancer Biol Ther 18:519-533
Liu, Yongqiang; Yuelling, Larra W; Wang, Yuan et al. (2017) Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion. Cancer Res 77:6692-6703
Vendramini-Costa, D├ębora Barbosa; Francescone, Ralph; Posocco, David et al. (2017) Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis. Carcinogenesis 38:51-63
Franco-Barraza, Janusz; Francescone, Ralph; Luong, Tiffany et al. (2017) Matrix-regulated integrin ?v?5 maintains ?5?1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife 6:
Darlow, Susan D; Heckman, Carolyn J; Munshi, Teja et al. (2017) Thirdhand smoke beliefs and behaviors among healthcare professionals. Psychol Health Med 22:415-424
Joseph, Giselle A; Lu, Min; Radu, Maria et al. (2017) Group I Paks Promote Skeletal Myoblast Differentiation In Vivo and In Vitro. Mol Cell Biol 37:
Heckman, C J; Handorf, E; Darlow, S D et al. (2017) Refinement of measures to assess psychosocial constructs associated with skin cancer risk and protective behaviors of young adults. J Behav Med 40:574-582
Heckman, Carolyn J; Handorf, Elizabeth A; Darlow, Susan D et al. (2017) An online skin cancer risk-reduction intervention for young adults: Mechanisms of effects. Health Psychol 36:215-225
Anthony, Sajitha A; Burrell, Anika L; Johnson, Matthew C et al. (2017) Reconstituted IMPDH polymers accommodate both catalytically active and inactive conformations. Mol Biol Cell :
Zhang, Yong; O'Leary, Monique N; Peri, Suraj et al. (2017) Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep 18:545-556

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