This is a revised proposal entitled "Cancer Epidemiology Training Program" (T32 CA09142-31). The previous review summarized three major limitations;1) unfilled post- and pre-doc positions;2) unsuccessful recruitment of underrepresented minority (URM) scholars;and (3) an unbalanced distribution of trainees among program faculty. We have made serious efforts which have led to the following changes: 1) all 7 positions were filled;2) 3 URM scholars were admitted;and 3) distribution of trainees was adjusted with increased faculty involvement. The objectives of this research training program are to continue to implement innovative, multidisciplinary, and collaborative research training in Cancer Epidemiology and to train five pre- and two post- doc trainees in an interdisciplinary program of cancer molecular and genetic epidemiology. In the last 5 years, this program has emphasized a multidisciplinary approach by providing instruction and mentoring in epidemiological methodology and molecular aspects of cancer. With continuous leadership, multidisciplinary faculty, a well-defined curriculum, and interdisciplinary research environments, we plan to continue to provide trainees the opportunity to gain experience in both cancer epidemiologic methods and molecular biology laboratory skills. This will allow trainees to utilize the knowledge of epidemiologic methods and molecular biology to elucidate genetic predisposition and susceptibility to cancer, to study effects of environmental exposures on cancer risk, to describe the natural history of cancer among high-risk individuals with inherited genetic mutations, and to evaluate gene-environment /gene-gene interactions on the risk of cancer. We will encourage trainees to make use of novel high-throughput technology in cancer epidemiological studies. The genetic molecular laboratory components as well as a newly constructed high-throughput genotyping laboratory in the Department of Epidemiology will facilitate this aspect of the training program. Program key faculty with NIH cancer-related research funds will provide research opportunities for trainees. Additional resources include patients in UCLA's Medical Center, the molecular, genetic, nutritional, and pathological laboratories within the UCLA Cancer Center, and the Los Angeles Cancer Surveillance programs. Special effort has been and will continue to be made to recruit qualified candidates from URM backgrounds and with MD training to post-doc positions. The Cancer Epidemiology Training Program has provided outstanding rigorous interdisciplinary training In epidemiology, statistics, and biology since 1975. Graduates of the program currently hold academic and research positions at leading universities and research institutions.
The cancer epidemiology training program has been emphasizing a multidisciplinary approach by providing instruction and mentoring to pre- and post-doctoral trainees in both epidemiological methodology and molecular genetic aspects of cancer and will continue to train five pre-doctoral and h/vo post-doctoral trainees in an interdisciplinary program of cancer molecular and genetic epidemiology.
|Zhang, Li Rita; Morgenstern, Hal; Greenland, Sander et al. (2015) Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium. Int J Cancer 136:894-903|
|Thompson, Caroline A; Arah, Onyebuchi A (2014) Selection bias modeling using observed data augmented with imputed record-level probabilities. Ann Epidemiol 24:747-53|
|Tarleton, Heather P; Chang, Shen-Chih; Park, Sungshim Lani et al. (2014) Genetic variation at 8q24, family history of cancer, and upper gastrointestinal cancers in a Chinese population. Fam Cancer 13:45-56|
|Kim, Claire H; Mu, Lina; Wu, Ming et al. (2014) Evaluating the evidence for the relationship between passive smoking and lung cancer. Int J Cancer 135:2232-3|
|Kim, Claire H; Lee, Yuan-Chin Amy; Hung, Rayjean J et al. (2014) Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO). Int J Cancer 135:1918-30|
|Marcotte, Erin L; Ritz, Beate; Cockburn, Myles et al. (2014) Exposure to infections and risk of leukemia in young children. Cancer Epidemiol Biomarkers Prev 23:1195-203|
|Jin, Zi-Yi; Wu, Ming; Han, Ren-Qiang et al. (2014) Household ventilation may reduce effects of indoor air pollutants for prevention of lung cancer: a case-control study in a Chinese population. PLoS One 9:e102685|
|Chang, Shen-Chih; Chang, Po-Yin; Butler, Brendan et al. (2014) Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population. PLoS One 9:e109235|
|Tarleton, Heather P; Smith, Lisa V; Zhang, Zuo-Feng et al. (2014) Utility of anthropometric measures in a multiethnic population: their association with prevalent diabetes, hypertension and other chronic disease comorbidities. J Community Health 39:471-9|
|Yang, Ying; Burke, Rita V; Jeon, Christie Y et al. (2014) Polymorphisms of peroxisome proliferator-activated receptors and survival of lung cancer and upper aero-digestive tract cancers. Lung Cancer 85:449-56|
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