The objective of the Training Program in Immunology at Sloan-Kettering Institution is to provide postdoctoral fellows a solid foundation in the field of Immunology and to direct their interests towards important aspects of the immune system and its response to infectious agents, self antigens, and cancer. Four postdoctoral positions are requested for this competitive renewal, which is unchanged from the past grant period. Duration of training will be 2 years. The Training Program provides Trainees with the intensive training, resources and experience necessary for them to develop successful careers in acidemia, government, and industry as independent researchers and leaders. Areas of research training cover lymphocyte development and biology, signaling, innate immunity, infectious immunity, transplantation immunity and cancer immunology. The objectives of the Training Program are achieved by providing a structured environment with intensive involvement in immunology research, further strengthened by attendance at weekly seminars and research-in-progress meetings, monthly research colloquium and translational research seminars and a yearly retreat. Trainees are also expected to participate in advanced courses covering contemporary topics of immunology and workshops on bioinformatics and grant writing skills. The Major part of the training comes from the research experience under the tutelage of preceptors who are engaged in excellent immunology research, with bearing on lymphocyte biology, cell signaling and transcription, innate immunity, infectious diseases, autoimmune diseases, transplantation and cancer. Trainees can also take advantage of many interdisciplinary collaborations between members of the Immunology Training Program and respected outside scientists, both locally and nationally.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009149-35
Application #
8094523
Study Section
Special Emphasis Panel (ZCA1-RTRB-A (M1))
Program Officer
Lim, Susan E
Project Start
1976-07-01
Project End
2012-07-31
Budget Start
2011-07-01
Budget End
2012-07-31
Support Year
35
Fiscal Year
2011
Total Cost
$110,831
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Yewdell, William T; Chaudhuri, Jayanta (2017) Molecular biology: RNA editing packs a one-two punch. Nature 542:420-421
Drané, Pascal; Brault, Marie-Eve; Cui, Gaofeng et al. (2017) TIRR regulates 53BP1 by masking its histone methyl-lysine binding function. Nature 543:211-216
Vaidyanathan, Bharat; Chaudhry, Ashutosh; Yewdell, William T et al. (2017) The aryl hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med 214:197-208
Oh, Soyoung A; Liu, Ming; Nixon, Briana G et al. (2017) Foxp3-independent mechanism by which TGF-? controls peripheral T cell tolerance. Proc Natl Acad Sci U S A 114:E7536-E7544
Casellas, Rafael; Basu, Uttiya; Yewdell, William T et al. (2016) Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity. Nat Rev Immunol 16:164-76
Stamatiades, Efstathios G; Tremblay, Marie-Eve; Bohm, Mathieu et al. (2016) Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages. Cell 166:991-1003
Abt, Michael C; McKenney, Peter T; Pamer, Eric G (2016) Clostridium difficile colitis: pathogenesis and host defence. Nat Rev Microbiol 14:609-20
Lupoli, Tania J; Fay, Allison; Adura, Carolina et al. (2016) Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK. Proc Natl Acad Sci U S A 113:E7947-E7956
Buffie, Charlie G; Bucci, Vanni; Stein, Richard R et al. (2015) Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile. Nature 517:205-8
Harris, Kendra K; Fay, Allison; Yan, Han-Guang et al. (2014) Novel imidazoline antimicrobial scaffold that inhibits DNA replication with activity against mycobacteria and drug resistant Gram-positive cocci. ACS Chem Biol 9:2572-83

Showing the most recent 10 out of 40 publications