The Training Program in Tumor Biology at Stanford University provides a multi-disciplinary postdoctoral research training and educational experience in translational and basic aspects of tumor biology for 8 qualified candidates with the Ph.D. and/or M.D. degree. The Program emphasizes investigative research in Tumor Biology under the guidance and supervision of faculty members from twelve basic and clinical departments in the School of Medicine (Biochemistry, Chemical &Systems Biology, Developmental Biology, Genetics, Medicine, Microbiology &Immunology, Molecular &Cellular Physiology, Pathology, Pediatrics, Radiation Oncology, and Structural Biology) as well as the Department of Biological Sciences in the School of Humanities and Sciences at Stanford University. Research areas of particular strength among the participating faculty and their trainees include: molecular mechanisms of transcriptional regulation;chromosomal DNA replication, repair, and recombination;cell cycle control;cancer stem cells;telomere dynamics;physiological mechanisms in normal and malignant cells;biochemical and molecular actions of oncoproteins and tumor suppressor proteins;tumor immunology and virology;immunogenetics and immunoregulation in human and murine model systems. In addition to intensive, mentored research training, which constitutes the central core of the Program, trainees: 1) meet annually with a small committee of Program and Departmental faculty for mentoring and career counseling;2) receive formal instruction in biomedical ethics, including guidelines for use of human and animal subjects;3) attend a variety of journal clubs and seminars, including a highly regarded Tumor Biology Seminar Series hosted by the Program, which invites eminent outside cancer investigators to talk, meet and dine with the trainees and their preceptors;4) attend and participate in an annual retreat held in conjunction with the interdepartmental Cancer Biology Pre-doctoral Training Program at Asilomar, California;and 5) attend and present results of original studies at national cancer research symposia. This program is the primary postdoctoral fellowship training venue in tumor biology that provides intellectual and scientific interactions and collaborations among the participating departments as well as the Stanford Cancer Center and the Stem Cell Institute in the School of Medicine. The preceptors in the Program constitute a major fraction of the institution's faculty with research interests in tumor biology and serve a pivotal role in supporting cancer educational and research initiatives at Stanford University.

Public Health Relevance

The Training Program in Tumor Biology at Stanford University provides postdoctoral research training for qualified candidates with the Ph.D. and/or M.D. degree. Trainees are prepared for future careers as scientific investigators by a multi-disciplinary research training and educational experience in translational and basic aspects of tumor biology.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009151-39
Application #
8459566
Study Section
Subcommittee G - Education (NCI)
Program Officer
Lim, Susan E
Project Start
1975-07-01
Project End
2015-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
39
Fiscal Year
2013
Total Cost
$330,553
Indirect Cost
$32,823
Name
Stanford University
Department
Pathology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Hodges, H Courtney; Stanton, Benjamin Z; Cermakova, Katerina et al. (2018) Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers. Nat Struct Mol Biol 25:61-72
Kim, Jeewon; Shin, June Ho; Chen, Che-Hong et al. (2017) Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor. Oncotarget 8:52345-52356
Miroshnikova, Y A; Rozenberg, G I; Cassereau, L et al. (2017) ?5?1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. Mol Biol Cell 28:2958-2977
Collins, Caitlin; Denisin, Aleksandra K; Pruitt, Beth L et al. (2017) Changes in E-cadherin rigidity sensing regulate cell adhesion. Proc Natl Acad Sci U S A 114:E5835-E5844
Braun, Simon M G; Kirkland, Jacob G; Chory, Emma J et al. (2017) Rapid and reversible epigenome editing by endogenous chromatin regulators. Nat Commun 8:560
Grigorian, Melina; DeBruhl, Heather; Lipsick, Joseph S (2017) The role of variant histone H2AV in Drosophila melanogaster larval hematopoiesis. Development 144:1441-1449
McCracken, M N; Tavaré, R; Witte, O N et al. (2016) Advances in PET Detection of the Antitumor T Cell Response. Adv Immunol 131:187-231
Stafford, Jason H; Hirai, Takahisa; Deng, Lei et al. (2016) Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization. Neuro Oncol 18:797-806
Zhang, Michael; Hutter, Gregor; Kahn, Suzana A et al. (2016) Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo. PLoS One 11:e0153550
Hodges, Courtney; Kirkland, Jacob G; Crabtree, Gerald R (2016) The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer. Cold Spring Harb Perspect Med 6:

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