Ever since its inception in 1978, the Stanford Cancer Biology Program aims to provide the best possible predoctoral and postdoctoral training in cancer research across the nation. One of the great strengths of the training program is its interdepartmental organization that gathers 62 faculty from 23 basic and clinical departments from the schools of Medicine and Humanities and Sciences at Stanford. The central core of our program is intensive and mentored research training. Our trainees conduct cutting-edge research in key areas of Cancer Biology such as cancer stem cells, animal models for cancer, tumor suppressor gene function, and the development of novel therapies to inhibit tumor growth and metastases. Research topics range from using Drosophila to identify genes involved in growth control, to more translational research in screening for small molecules inhibitors that selectively kill tumor cells, to clinical research that applies microarray technology to determine patients'prognostic outcome from tumor gene-expression profiling. Predoctoral trainees build a solid foundation in the discipline of Cancer Biology through required and elective coursework, laboratory research, grant and thesis writing. Postdoctoral trainees also receive rigorous training through research, attending scientific seminars in Cancer Biology, writing fellowship applications and research manuscripts. All trainees are required to present their research at the Annual Asilomar Conference where the entire Stanford Cancer Biology Community gathers to share data and exchange ideas. Trainees are also highly encouraged to attend and present at national and international conferences. All trainees receive formal instructions on biomedical ethics. Trainees'research progress are reviewed annually. In addition, all trainees have the opportunity to meet the invited scientific leaders to discuss about their research, career goals and opportunities. Besides the outstanding faculty mentorship, students are now exposed to the state of the art teaching facilities and research labs that foster extensive research collaborations that arise due to the rapid advancement of cancer research. Finally, with creation of the Stanford Cancer and Stem Cell Institute and the application to become a NCI designated Cancer Center, the Cancer Biology training program will serve an even more prominent role in supporting cancer education and research at Stanford.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009302-35
Application #
8123458
Study Section
Special Emphasis Panel (ZCA1-RTRB-A (M1))
Program Officer
Lim, Susan E
Project Start
1977-09-15
Project End
2013-06-30
Budget Start
2011-07-01
Budget End
2013-06-30
Support Year
35
Fiscal Year
2011
Total Cost
$856,459
Indirect Cost
Name
Stanford University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Kariolis, Mihalis S; Miao, Yu Rebecca; Diep, Anh et al. (2017) Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest 127:183-198
Chuang, Chen-Hua; Greenside, Peyton G; Rogers, Zoë N et al. (2017) Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis. Nat Med 23:291-300
García-Nieto, Pablo E; Schwartz, Erin K; King, Devin A et al. (2017) Carcinogen susceptibility is regulated by genome architecture and predicts cancer mutagenesis. EMBO J 36:2829-2843
Jeong, Youngtae; Hoang, Ngoc T; Lovejoy, Alexander et al. (2017) Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance. Cancer Discov 7:86-101
Spitzer, Matthew H; Carmi, Yaron; Reticker-Flynn, Nathan E et al. (2017) Systemic Immunity Is Required for Effective Cancer Immunotherapy. Cell 168:487-502.e15
Kunimoto, Koshi; Bayly, Roy D; Vladar, Eszter K et al. (2017) Disruption of Core Planar Cell Polarity Signaling Regulates Renal Tubule Morphogenesis but Is Not Cystogenic. Curr Biol 27:3120-3131.e4
Dulken, Ben W; Leeman, Dena S; Boutet, Stéphane C et al. (2017) Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage. Cell Rep 18:777-790
Han, Kyuho; Jeng, Edwin E; Hess, Gaelen T et al. (2017) Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. Nat Biotechnol 35:463-474
Chang, Junlei; Mancuso, Michael R; Maier, Carolina et al. (2017) Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. Nat Med 23:450-460
Benham-Pyle, Blair W; Sim, Joo Yong; Hart, Kevin C et al. (2016) Increasing ?-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis. Elife 5:

Showing the most recent 10 out of 323 publications