The main objective of the training program of the Science Park-Research Division (SPRD) of the University of Texas M.D. Anderson Cancer Center is to prepare trainees to carry out independent and productive research in carcinogenesis and mutagenesis. This program supports five postdoctoral fellows and two graduate students. Trainees who are accepted into the program will have the opportunity to work in the laboratory of a mentor most closely aligned with their research interests. Collaboration occurs at every level in the multidisciplinary research programs at SPRD and will continue to be stressed in the research training of graduate students and postdoctoral fellows. Graduate students will be trained to conduct independent and creative research which contributes new knowledge in carcinogenesis or mutagenesis. Postdoctoral trainees will be encouraged to develop their expertise in areas beyond those established during their predoctoral training. Emphasis is placed on recruiting a diverse and interactive group of trainees. In addition to training in carcinogenesis and mutagenesis research, the trainees also will have the opportunity to expand their knowledge of various areas of cancer research by participating in didactic lecture courses, seminars, journal clubs, meetings and retreats. In addition, all trainees are required to attend a course """"""""The Ethical Dimensions in the Biomedical Sciences"""""""" to provide instruction in the responsible conduct of research.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Program Officer
Lim, Susan E
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas MD Anderson Cancer Center
Organized Research Units
United States
Zip Code
Rycaj, Kiera; Cho, Eun Jeong; Liu, Xin et al. (2016) Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells. Oncotarget 7:14220-40
Liu, Ruifang; Liu, Can; Zhang, Dingxiao et al. (2016) miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells. Oncotarget 7:56628-56642
Wyatt, David W; Feng, Wanjuan; Conlin, Michael P et al. (2016) Essential Roles for Polymerase ?-Mediated End Joining in the Repair of Chromosome Breaks. Mol Cell 63:662-673
Mitchell, David; Paniker, Lakshmi; Lin, Kevin et al. (2015) Interspecific variation in the repair of UV damaged DNA in the genus Xiphophorus as a factor in the decline of the Rio Grande Platyfish. Photochem Photobiol 91:486-92
Tomida, Junya; Takata, Kei-ichi; Lange, Sabine S et al. (2015) REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ?. Nucleic Acids Res 43:1000-11
Aldaz, C Marcelo; Ferguson, Brent W; Abba, Martin C (2014) WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies. Biochim Biophys Acta 1846:188-200
Yousefzadeh, Matthew J; Wyatt, David W; Takata, Kei-Ichi et al. (2014) Mechanism of suppression of chromosomal instability by DNA polymerase POLQ. PLoS Genet 10:e1004654
Angel, Joe M; Abel, Erika L; Riggs, Penny K et al. (2014) Fine mapping reveals that promotion susceptibility locus 1 (Psl1) is a compound locus with multiple genes that modify susceptibility to skin tumor development. G3 (Bethesda) 4:1071-9
Reeh, Kaitlin A G; Cardenas, Kim T; Bain, Virginia E et al. (2014) Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development 141:2950-8
Lin, Yi-Chen; Richburg, John H (2014) Characterization of the role of tumor necrosis factor apoptosis inducing ligand (TRAIL) in spermatogenesis through the evaluation of trail gene-deficient mice. PLoS One 9:e93926

Showing the most recent 10 out of 66 publications