The Department of Surgery at Washington University School of Medicine (WUSM) is one of the nation's leading academic surgery departments, with a strong and uncompromising commitment to training the next generation of academic surgeon-scientists. The Surgical Oncology Basic Science and Translational Research Training Program is a critical component of this overall training goal. The current T32 application will provide surgical trainees from general surgery and other surgical subspecialties the opportunity to develop essential skill sets in basic science, translational, and public health research. The Surgical Oncology Research Training Program has evolved in parallel with a dynamic training environment at WUSM, and currently takes advantage of unique resources in the Department of Surgery, the Siteman Cancer Center, the Division of Biology and Biomedical Sciences, the Institute of Clinical and Translational Sciences, and the Department of Surgery's Division of Public Health Sciences to develop customized and highly structured formal didactic and mentored research experiences for individual surgical trainees. The success of the program is evidenced by the important research accomplishments made by trainees working with program faculty, and the long-term success of trainees in academic medicine. Of note, 5/8 trainees (63%) who have completed the research training program and their clinical training in the last ten years, and 35/60 trainees (58%) who have competed the program since its inception, remain in academic medicine, many with independent funding. Important changes to the Surgical Oncology Research Training Program in this competitive review include additions to the program leadership, development of two distinct research tracks (basic science track, and translational research/public health/clinical effectiveness track), and reduction in the number of training slots to allow for an increase in the tuition budget. These changes will ensure that the Surgical Oncology Research Training Program maintains excellence at the forefront of two different surgical oncology research paradigms, basic science research, and translational/public health/clinical effectiveness research. NCI support will allow WUSM to continue this highly successful research training program, providing the next generation of surgeon- scientists with the research training required to succeed in an increasingly competitive research environment.
Surgeon-scientists are in a unique position to facilitate the clinical translation of basic science research discoveries, with the potential for significant improvements in patient care. The Surgical Oncology Basic Science and Translational Research Training Program will provide surgical trainees from general surgery and other surgical subspecialties the opportunity to develop essential skill sets in basic science, translational, and public health research.
|Sanford, Dominic E; Sanford, Angela M; Fields, Ryan C et al. (2014) Severe nutritional risk predicts decreased long-term survival in geriatric patients undergoing pancreaticoduodenectomy for benign disease. J Am Coll Surg 219:1149-56|
|Hashim, Yassar M; Spitzer, Dirk; Vangveravong, Suwanna et al. (2014) Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134. Mol Oncol 8:956-67|
|Sanford, Dominic E; Olsen, Margaret A; Bommarito, Kerry M et al. (2014) Association of discharge home with home health care and 30-day readmission after pancreatectomy. J Am Coll Surg 219:875-86.e1|
|Zhu, Yu; Knolhoff, Brett L; Meyer, Melissa A et al. (2014) CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Res 74:5057-69|
|Fayanju, Oluwadamilola M; Kraenzle, Susan; Drake, Bettina F et al. (2014) Perceived barriers to mammography among underserved women in a Breast Health Center Outreach Program. Am J Surg 208:425-34|
|Rowland, Kathryn J; Diaz-Miron, Jose; Guo, Jun et al. (2014) CXCL5 is required for angiogenesis, but not structural adaptation after small bowel resection. J Pediatr Surg 49:976-80; discussion 980|
|Fayanju, Oluwadamilola M; Jeffe, Donna B; Elmore, Leisha et al. (2014) Breast cancer patients' experiences within and outside the safety net. J Surg Res 190:126-33|
|Kooby, David A; Lad, Neha L; Squires 3rd, Malcolm H et al. (2014) Value of intraoperative neck margin analysis during Whipple for pancreatic adenocarcinoma: a multicenter analysis of 1399 patients. Ann Surg 260:494-501; discussion 501-3|
|Hashim, Yassar M; Trinkaus, Kathryn M; Linehan, David C et al. (2014) Regional lymphadenectomy is indicated in the surgical treatment of pancreatic neuroendocrine tumors (PNETs). Ann Surg 259:197-203|
|Fayanju, Oluwadamilola M; Stoll, Carolyn R T; Fowler, Susan et al. (2013) Geographic and temporal trends in the management of occult primary breast cancer: a systematic review and meta-analysis. Ann Surg Oncol 20:3308-16|
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