This T32 will train 2 oncology fellows per year in """"""""Clinical Translational and Population Science"""""""" at the University of North Carolina Chapel Hill. Trainees will obtain the fundamental competencies via didactics, hands-on research, and preparation of scholarly products needed to begin careers in clinical translational research or population sciences at research-intensive academic centers. Trainees will also be prepared to compete for research funding from a variety of sources, including, if they remain at UNC, the Paul Calabrese K12. ? ? Leadership. The program will be directed by Dr. Richard Goldberg, Chief of the Division of Hematology/Oncology and UNC Hospitals Cancer Center and Associate Directors, Dr Shelton Earp, Director of the Lineberger Comprehensive Cancer Center, and Dr Paul Godley, Associate Professor in Oncology and the School of Public Health. Faculty: There are 39 talented faculty mentors representing clinical, basic, and population research. Mentors have been selected based on research program, funding, and training experience. Resources include an 800 bed tertiary care hospital, an inpatient general clinical research center, extensive research laboratory facilities, and in 2009, the North Carolina Cancer Hospital. Outstanding programs available to trainees include thoracic, genitourinary, dermatologic, and neuro oncology as well as gastrointestinal and breast cancer research programs integrated with SPORE funding. Lineberger Cancer Research programs can be accessed that involve cell biology, immunology, carcinogenesis, molecular therapeutics, virology, genetics, cancer prevention and control and epidemiology. Trainees: Trainees will be selected from a competitive pool of applicants drawn from the adult and pediatric oncology training programs. Applications are reviewed by a steering committee comprising leadership and fellowship directors. Program: Each trainee selected is assigned at least 2 mentors with each mentor representing a different spectrum of research. Trainees will spend 75% of their time attending required K30 courses and optional didactics, developing and conducting their research project(s) under their mentors' supervision, training in Responsible Conduct of Research, and learning how to present their research in talks, posters, manuscripts, and first grant applications. Trainees in both tracks will participate in the Translational Seminar Series which has been especially developed for this program. This multi-year seminar presents the emerging discoveries in oncology organized across 30 topics and is not available elsewhere at UNC. Evaluation of the trainees, faculty and the program as a whole will be done on an annual basis by all of the participants, the steering committee and by the internal and external advisory committees. ? ? This training will be unique at UNC and will help ensure that our oncology trainees are prepared to begin research careers that will ultimately improve patient outcomes. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
1T32CA128590-01A1
Application #
7502810
Study Section
Subcommittee G - Education (NCI)
Program Officer
Myrick, Dorkina C
Project Start
2008-09-01
Project End
2013-08-31
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
1
Fiscal Year
2008
Total Cost
$128,532
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Cobran, Ewan K; Chen, Ronald C; Overman, Robert et al. (2016) Racial Differences in Diffusion of Intensity-Modulated Radiation Therapy for Localized Prostate Cancer. Am J Mens Health 10:399-407
Tichy, J R; Deal, A M; Anders, C K et al. (2015) Race, response to chemotherapy, and outcome within clinical breast cancer subtypes. Breast Cancer Res Treat 150:667-74
Penn, Dolly C; Chang, YunKyung; Meyer, Anne-Marie et al. (2015) Provider-based research networks may improve early access to innovative colon cancer treatment for African Americans treated in the community. Cancer 121:93-101
Penn, Dolly C; Stitzenberg, Karyn B; Cobran, Ewan K et al. (2014) Provider-based research networks demonstrate greater hospice use for minority patients with lung cancer. J Oncol Pract 10:e182-90
Chism, David D; Rathmell, W Kimryn (2014) Seeing the forest for the trees: kidney oncogenomes in relation to therapeutic outcomes. Clin Cancer Res 20:1721-3
Stitzenberg, Karyn B; Sanoff, Hanna K; Penn, Dolly C et al. (2013) Practice patterns and long-term survival for early-stage rectal cancer. J Clin Oncol 31:4276-82
Meyer, Anne-Marie; Reeder-Hayes, Katherine E; Liu, Huan et al. (2013) Differential receipt of sentinel lymph node biopsy within practice-based research networks. Med Care 51:812-8
Li, Mingqing; Gerber, David A; Koruda, Mark et al. (2012) Hepatocelluar carcinoma associated with attenuated familial adenomatous polyposis: a case report and review of the literature. Clin Colorectal Cancer 11:77-81
Li, Mingqing; Kim, William Y (2011) Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL. J Cell Mol Med 15:187-95