EXCEED THE SPACE PROVIDED. This is an application for renewal of an interdisciplinary Drug Abuse Research Training Program, entitled Training in Neurobehavior/Neuroimmune Addiction Research. This training program, which combined the strengths of two NIDA-funded programs at the University of Minnesota entitled Training in Drug Abuse and Neurobehavioral Pharmacology (T32 DA07097-20) and Training in Psychoneuroimmunology and Substance Abuse (T32 DA07239-10), has been in existence for the past 4 years. The proposed training program fulfills a well-recognized need of training biomedical scientists at the pre- and postdoctoral levels in an interdisciplinary field that focuses on the interactions of drugs of abuse with the nervous and immune systems and integrates the effects of these interactions with behavioral counterparts. To this end, training which begins at the predoctoral level and provides coherent exposure to the various disciplines that constitute this field, will make an especially important contribution to the development of this field. Training scientists in such an interdisciplinary field is only available at a few institutions. A talented group of neuroscientists, psychologists, pharmacologists, immunologists and microbiologists are assembled at the University of Minnesota and affiliated institutions to participate in the proposed interdisciplinary training program. The program combines the talents and skills of laboratory-based scientists with clinical faculty, allowing the program to attract outstanding predoctoral students and postdoctoral fellows. We have in place a significant number of funded faculty working in pertinent areas of research with a commitment to training predoctoral students and postdoctoral fellows. All the elements of training are in place: a formal curriculum for predoctoral study including formal courses in Neuro-lmmune Interactions and Neuropschopharmacology, a seminar program, and most importantly linkages with faculty across the relevant disciplines. This training program will foster development of scientists who have the knowledge and experience for research careers similar to trainees who have already completed training and now hold positions in academic and government institutions or industry. To fulfill our training mission, 12 predoctoral and 9 postdoctoral positions are requested. PERFORMANCE SITE ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Institutional National Research Service Award (T32)
Project #
3T32DA007097-25S1
Application #
7279087
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Lawrence, Diane M
Project Start
1979-01-01
Project End
2007-06-30
Budget Start
2005-07-01
Budget End
2007-06-30
Support Year
25
Fiscal Year
2006
Total Cost
$263,229
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Other Clinical Sciences
Type
Schools of Veterinary Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Clayton, Jonathan B; Al-Ghalith, Gabriel A; Long, Ha Thang et al. (2018) Associations Between Nutrition, Gut Microbiome, and Health in A Novel Nonhuman Primate Model. Sci Rep 8:11159
Laudenbach, Megan; Baruffaldi, Federico; Robinson, Christine et al. (2018) Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose. Sci Rep 8:5508
Harris, Andrew C; Muelken, Peter; Haave, Zach et al. (2018) Propylene glycol, a major electronic cigarette constituent, attenuates the adverse effects of high-dose nicotine as measured by intracranial self-stimulation in rats. Drug Alcohol Depend 193:162-168
Harris, Andrew C; Muelken, Peter; Smethells, John R et al. (2018) Effects of nicotine-containing and ""nicotine-free"" e-cigarette refill liquids on intracranial self-stimulation in rats. Drug Alcohol Depend 185:1-9
Martin, Jessica L; Mendonça, Luiza M; Marusinec, Rachel et al. (2018) Critical Role of the Human T-Cell Leukemia Virus Type 1 Capsid N-Terminal Domain for Gag-Gag Interactions and Virus Particle Assembly. J Virol 92:
Leavens, Eleanor L S; Meier, Ellen; Tackett, Alayna P et al. (2018) The impact of a brief cessation induction intervention for waterpipe tobacco smoking: A pilot randomized clinical trial. Addict Behav 78:94-100
Swain, Yayi; Muelken, Peter; LeSage, Mark G et al. (2018) Locomotor activity does not predict individual differences in morphine self-administration in rats. Pharmacol Biochem Behav 166:48-56
Chernick, Dustin; Ortiz-Valle, Stephanie; Jeong, Angela et al. (2018) High-density lipoprotein mimetic peptide 4F mitigates amyloid-?-induced inhibition of apolipoprotein E secretion and lipidation in primary astrocytes and microglia. J Neurochem 147:647-662
Claborn, Kasey R; Meier, Ellen; Miller, Mary Beth et al. (2018) Improving adoption and acceptability of digital health interventions for HIV disease management: a qualitative study. Transl Behav Med 8:268-279
Swalve, Natashia; Smethells, John R; Younk, Rebecca et al. (2018) Sex-specific attenuation of impulsive action by progesterone in a go/no-go task for cocaine in rats. Psychopharmacology (Berl) 235:135-143

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