This proposal will establish a unique training program in a developing area of transdisciplinary research, co-occurring substance use and other mental disorders (COD). The need for this scientific focus is vital given that COD is more the norm than the exception among those with addictive disorders. The philosophy of this program asserts that to effectively impact the problems of addiction and mental illness, one must be fully aware of their co-existence, etiologies, phenomenology, and clinical manifestations. Moreover, knowledge of clinical approaches and the healthcare systems that serve those with addiction and mental illness is necessary to inform the questions to be asked in laboratory and clinical research studies. Embracing COD as a primary perspective is not a widely accepted approach for the training of scientists. Of NIDA's approximate sixty T32 programs, none include the words co-morbidity, dual diagnosis, or other indicators of a focus on COD. Establishing programs that prioritize training in this area will lead to the development of advanced methods for finding innovative strategies for serving those with COD. We propose to develop such a program by utilizing the unique resources and opportunities available at Dartmouth. Six interconnected groups will provide research opportunities in social, behavioral, and neurobiological mechanisms, treatment development (psychosocial and pharmacological), technology-assisted treatment and dissemination, and health services practices and implementation. Faculty include preeminent leaders in COD research, MD and PhD investigators with strong histories of training scientists, and a team of support faculty committed to establishing a structured training program in COD. Research teams include neuroscientists, behavioral health technologists, clinical trials and contingency management experts, anthropologists, statisticians, economists, and family therapists. Currently the faculty has 27 NIH-funded projects (NIDA [12], NIAAA [4], NIMH [8], NCI [2];NICHD [1]), and multiple foundation, Department of Education, and VA supported studies. Predoctoral and postdoctoral students mentored by core faculty in the past 10 years have co-authored over 150 publications related to their training activities and were first author on approximately 50% of those. This program will train 5-7 predoctoral and 9-11 postdoctoral students in the initial funding period. The stellar reputation of the faculty and participating research programs, in concert with rigorous criteria for trainee selection and a strong commitment to attracting diverse trainees, will ensure the development of scientists with greater knowledge about the scope of issues that science must address to effectively impact addiction and mental illness. This cohort will be more equipped with broad areas of expertise and a commitment to multidisciplinary approaches to their questions of interest.

Public Health Relevance

This proposed training program is highly relevant to public health because it will train a new cohort of scientists to conceptualize and research addiction from a primary perspective that substance use disorders most often co-occur with other types of mental disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Institutional National Research Service Award (T32)
Project #
1T32DA037202-01
Application #
8667205
Study Section
Special Emphasis Panel (ZDA1)
Program Officer
Onken, Lisa
Project Start
2014-07-01
Project End
2019-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
1
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Hanover
State
NH
Country
United States
Zip Code
03755
Drake, Robert E; Luciano, Alison E; Mueser, Kim T et al. (2016) Longitudinal Course of Clients With Co-occurring Schizophrenia-Spectrum and Substance Use Disorders in Urban Mental Health Centers: A 7-Year Prospective Study. Schizophr Bull 42:202-11
Lee, Dustin C; Crosier, Benjamin S; Borodovsky, Jacob T et al. (2016) Online survey characterizing vaporizer use among cannabis users. Drug Alcohol Depend 159:227-33
Borodovsky, Jacob T; Crosier, Benjamin S; Lee, Dustin C et al. (2016) Smoking, vaping, eating: Is legalization impacting the way people use cannabis? Int J Drug Policy 36:141-7
Nordstrom, Benjamin R; Saunders, Elizabeth C; McLeman, Bethany et al. (2016) Using a Learning Collaborative Strategy With Office-based Practices to Increase Access and Improve Quality of Care for Patients With Opioid Use Disorders. J Addict Med 10:117-23
Babbin, Steven F; Stanger, Catherine; Scherer, Emily A et al. (2016) Identifying treatment response subgroups for adolescent cannabis use. Addict Behav 59:72-9
Stanger, Catherine; Lansing, Amy Hughes; Budney, Alan J (2016) Advances in Research on Contingency Management for Adolescent Substance Use. Child Adolesc Psychiatr Clin N Am 25:645-59
Marsch, Lisa A; Moore, Sarah K; Borodovsky, Jacob T et al. (2016) A randomized controlled trial of buprenorphine taper duration among opioid-dependent adolescents and young adults. Addiction 111:1406-15
Saunders, Elizabeth C; McGovern, Mark P; Lambert-Harris, Chantal et al. (2015) The impact of addiction medications on treatment outcomes for persons with co-occurring PTSD and opioid use disorders. Am J Addict 24:722-31
Lee, Dustin C; Stanger, Catherine; Budney, Alan J (2015) A comparison of delay discounting in adolescents and adults in treatment for cannabis use disorders. Exp Clin Psychopharmacol 23:130-7
Babbin, Steven F; Velicer, Wayne F; Paiva, Andrea L et al. (2015) Replicating cluster subtypes for the prevention of adolescent smoking and alcohol use. Addict Behav 40:57-65

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