Since its inception, the Monell Center has enjoyed a successful multi-level interdisciplinary training program in the chemical senses which consists of education, training and research by high school and undergraduate students, pre- and postdoctoral trainees and fellows and visiting scientists. This application requests funds to defray costs of the postdoctoral components only. Fellows are accepted into the Program from various disciplines to be cross-trained under the supervision of preceptors. The immediate goal of the Program is to familiarize young scientists (we seek support for 2 level-0, 2 level 1 and 1 level-2 fellows) with the results of previous and on-going investigations and to provide an environment that is conducive to fruitful independent research. The long-term goal is to provide a pool of well-trained scientists who are capable of maintaining a course of fundamental research in the chemical senses or who can utilize their training in applied and/or clinical settings. Relevance: In the Training Program, irrespective of previous background, fellows are exposed to the many disciplines found within the Center, from molecular genetics to whole organism research with animals and human behavior. Currently there are 23 faculty members employing these myriad experimental approaches in their quests for further understanding of chemosensory systems and their impact on daily lives. This is done at the vary basic level, in clinical settings via access to patients in the Monell-Jefferson Chemosensory Clinical Research Center, through the use mammalian models of chemosensory function and dysfunction, and via in vitro test systems.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
5T32DC000014-31
Application #
7840420
Study Section
Communication Disorders Review Committee (CDRC)
Program Officer
Sklare, Dan
Project Start
1979-07-01
Project End
2012-03-02
Budget Start
2010-07-01
Budget End
2012-03-02
Support Year
31
Fiscal Year
2010
Total Cost
$190,151
Indirect Cost
Name
Monell Chemical Senses Center
Department
Type
DUNS #
088812565
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Ibarra-Soria, Ximena; Nakahara, Thiago S; Lilue, Jingtao et al. (2017) Variation in olfactory neuron repertoires is genetically controlled and environmentally modulated. Elife 6:
Bobowski, Nuala; Reed, Danielle R; Mennella, Julie A (2016) Variation in the TAS2R31 bitter taste receptor gene relates to liking for the nonnutritive sweetener Acesulfame-K among children and adults. Sci Rep 6:39135
Lewandowski, Brian C; Sukumaran, Sunil K; Margolskee, Robert F et al. (2016) Amiloride-Insensitive Salt Taste Is Mediated by Two Populations of Type III Taste Cells with Distinct Transduction Mechanisms. J Neurosci 36:1942-53
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Prokop-Prigge, Katharine A; Greene, Kathryn; Varallo, Lauren et al. (2016) The Effect of Ethnicity on Human Axillary Odorant Production. J Chem Ecol 42:33-9
Mennella, Julie A; Bobowski, Nuala K; Reed, Danielle R (2016) The development of sweet taste: From biology to hedonics. Rev Endocr Metab Disord 17:171-8
Bobowski, Nuala K; Mennella, Julie A (2015) Disruption in the Relationship between Blood Pressure and Salty Taste Thresholds among Overweight and Obese Children. J Acad Nutr Diet 115:1272-82
Bobowski, Nuala (2015) Shifting human salty taste preference: Potential opportunities and challenges in reducing dietary salt intake of Americans. Chemosens Percept 8:112-116
Prokop-Prigge, Katharine A; Mansfield, Corrine J; Parker, M Rockwell et al. (2015) Ethnic/racial and genetic influences on cerumen odorant profiles. J Chem Ecol 41:67-74

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