The purpose of the proposed competing renewal for "Research Training in Otolaryngology" is to provide a two-year period of uninterrupted research training for one individual per year during the course of clinical residency training in otolaryngology-head and neck surgery. As in the past, the clinical training program at Harvard/Massachusetts Eye and Ear Infirmary has two separate tracks, a clinical track and a research track, and it is in that latter research track that training will be supported. The educational objective of the training program is to prepare the selected trainees for an academic career in otolaryngology-head and neck surgery and to prepare them to successfully compete for peer-reviewed funding for research. The program provides opportunity for research training in established laboratories under the mentorship of individuals with a track record of peer-reviewed research support in a wide variety of research laboratories in the Department of Otolaryngology at the Massachusetts Eye and Ear Infirmary, its affiliated hospitals, including Children's Hospital of Boston, The Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, and the Massachusetts Institute of Technology. The research opportunities include a wide variety of basic, clinical and translational research in hearing, balance, laryngology and voice, molecular biology and genetics, head and neck neoplasia, laser technology, and neuroprostheses. The applicants will be drawn from a pool of approximately 230 applicants on a yearly basis for residency training in otolaryngology, which includes specific recruitment of individuals from underrepresented racial/ethnic groups. The educational program includes training in responsible conduct of research and specific mentorship in the application process for peer-reviewed funding. The application pool will be interviewed by a residency selection committee which includes representation from members of the research community.

Public Health Relevance

The true benefit of biomedical research to public health depends upon swift and efficient translation of scientific discoveries into the healthcare domain. This translation is accomplished first and foremost by the cadre of bilingual clinician-scientist who are at home in both the world of science and the world of clinical medicine. Our program aims precisely to nurture the development of such clinician-scientists in the field of otolaryngology - head and neck surgery.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
2T32DC000020-24
Application #
8474161
Study Section
Special Emphasis Panel (ZDC1-SRB-R (37))
Program Officer
Sklare, Dan
Project Start
1985-07-01
Project End
2018-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
24
Fiscal Year
2013
Total Cost
$121,751
Indirect Cost
$8,619
Name
Massachusetts Eye and Ear Infirmary
Department
Type
DUNS #
073825945
City
Boston
State
MA
Country
United States
Zip Code
02114
Bonilla-Velez, Juliana; Mroz, Edmund A; Hammon, Rebecca J et al. (2013) Impact of human papillomavirus on oropharyngeal cancer biology and response to therapy: implications for treatment. Otolaryngol Clin North Am 46:521-43
Benoit, Margo McKenna; Raij, Tommi; Lin, Fa-Hsuan et al. (2010) Primary and multisensory cortical activity is correlated with audiovisual percepts. Hum Brain Mapp 31:526-38
Nakajima, Hideko Heidi; Merchant, Saumil N; Rosowski, John J (2010) Performance considerations of prosthetic actuators for round-window stimulation. Hear Res 263:114-9
Nakajima, Hideko Heidi; Dong, Wei; Olson, Elizabeth S et al. (2010) Evaluation of round window stimulation using the floating mass transducer by intracochlear sound pressure measurements in human temporal bones. Otol Neurotol 31:506-11
Peng, Anthony W; Belyantseva, Inna A; Hsu, Patrick D et al. (2009) Twinfilin 2 regulates actin filament lengths in cochlear stereocilia. J Neurosci 29:15083-8
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Nakajima, Hideko Heidi; Dong, Wei; Olson, Elizabeth S et al. (2009) Differential intracochlear sound pressure measurements in normal human temporal bones. J Assoc Res Otolaryngol 10:23-36
Chien, Wade; Northrop, Clarinda; Levine, Stephen et al. (2009) Anatomy of the distal incus in humans. J Assoc Res Otolaryngol 10:485-96
Rosowski, John J; Nakajima, Hideko H; Merchant, Saumil N (2008) Clinical utility of laser-Doppler vibrometer measurements in live normal and pathologic human ears. Ear Hear 29:3-19
Nakajima, Hideko Heidi; Ravicz, Michael E; Rosowski, John J et al. (2005) Experimental and clinical studies of malleus fixation. Laryngoscope 115:147-54

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