Our program aims to train and develop physician-scientists who will advance the field of otolaryngology-head and neck surgery. Our subspecialty requires a wide variety of expertise and scientific strategies for understanding and treating communication disorders and diseases of the head and neck. These diseases can limit survival, and more broadly affect the ability to relate to family, workplace and society at large.
We aim to provide the scientific training, as well as communication and administrative skills that will enabl our graduates to become creative contributors to the future of otolaryngology and the treatment of associated communication disorders. One significant indicator of success, and a point of great pride, is the number of trainees who have gone on to academic careers at Hopkins and elsewhere, including several who are now among the faculty of this training grant. Two residents per year enter into 2 years of research training in their third year of residency. These trainees can choose from a wide, and deep, selection of research programs both within the department, and in associated laboratories at Hopkins and elsewhere. The topics include, but are not limited to: molecular biology of head and neck cancers, basic mechanisms of, and therapeutic innovation for dizziness and balance, studies of the auditory nervous system including utilization and outcomes of cochlear implantation, pathogenesis of sinusitis, epidemiologic and genomic association studies.
We aim to educate enthusiastic, inquisitive, critical, and knowledgeable young investigators who can pose and then answer significant questions and who will be able to conduct successful, independent research careers in academic medicine.

Public Health Relevance

This is a training grant application to support 2 years of research for 2 trainees in the Oto-HNS residency. These trainees spend full-time learning and carrying out scientific research in the laboratory of participating faculty, with a view to becomin independent clinician-scientists.

National Institute of Health (NIH)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZDC1)
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Sklare, Dan
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Johns Hopkins University
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United States
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Emmett, Susan D; Francis, Howard W (2015) The socioeconomic impact of hearing loss in U.S. adults. Otol Neurotol 36:545-50
Schierl, Michael; Patel, Daxesh; Ding, Wanhong et al. (2014) Tobacco smoke-induced immunologic changes may contribute to oral carcinogenesis. J Investig Med 62:316-23
Iyengar, Neil M; Kochhar, Amit; Morris, Patrick G et al. (2014) Impact of obesity on the survival of patients with early-stage squamous cell carcinoma of the oral tongue. Cancer 120:983-91
Genther, Dane J; Kandil, Emad H; Noureldine, Salem I et al. (2014) Correlation of final evoked potential amplitudes on intraoperative electromyography of the recurrent laryngeal nerve with immediate postoperative vocal fold function after thyroid and parathyroid surgery. JAMA Otolaryngol Head Neck Surg 140:124-8
Emmett, Susan D; West Jr, Keith P (2014) Gestational vitamin A deficiency: a novel cause of sensorineural hearing loss in the developing world? Med Hypotheses 82:6-10
Mydlarz, Wojciech; Uemura, Mamoru; Ahn, Sun et al. (2014) Clusterin is a gene-specific target of microRNA-21 in head and neck squamous cell carcinoma. Clin Cancer Res 20:868-77
Ward, Bryan K; Tan, Grace X-J; Roberts, Dale C et al. (2014) Strong static magnetic fields elicit swimming behaviors consistent with direct vestibular stimulation in adult zebrafish. PLoS One 9:e92109
Kochhar, Amit; Kopelovich, Levy; Sue, Erika et al. (2014) p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling. Cancer Prev Res (Phila) 7:596-606
Emmett, Susan D; Francis, Howard W (2014) Bilateral hearing loss is associated with decreased nonverbal intelligence in US children aged 6 to 16 years. Laryngoscope 124:2176-81
Ward, Bryan K; Wenzel, Angela; Ritzl, Eva K et al. (2013) Near-dehiscence: clinical findings in patients with thin bone over the superior semicircular canal. Otol Neurotol 34:1421-8

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