The overall objective of this program is to train physicians in relevant scientific disciplines for a career that combines laboratory research with clinical otolaryngology. This unique Research Training Program at the University of Pittsburgh enables trainees to develop both basic research and clinical skills. Potential trainees are selected from the outstanding pool of candidates that apply to the Residency Program in Otolaryngology. Trainees can select preceptors with research interests that span a variety of disciplines and rotate through two potential training laboratories prior to entering the protected research years. The PGY-5 and PGY-6 years are spent in the preceptor's laboratory. During this protected research time, trainees also participate in a formal Clinical Research Training Program as part of the Clinical and Translational Science Institute (CTSI) at the University of Pittsburgh (KL2RR024154). Following the two contiguous years in the laboratory, trainees will return to the clinic for their final year of residency. One new trainee is admitted to our program each year. To provide a dedicated year of otolaryngology research experience to predoctoral candidates, a second trainee is recruited annually from the University of Pittsburgh School of Medicine. The purpose of this second training position is to attract talented medical students into the field of otolaryngology. By providing these medical students with an intensive, year long laboratory research experience, they are uniquely poised to secure an otolaryngology residency position at a research oriented program.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
5T32DC000066-10
Application #
8270546
Study Section
Communication Disorders Review Committee (CDRC)
Program Officer
Sklare, Dan
Project Start
2001-07-01
Project End
2013-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
10
Fiscal Year
2012
Total Cost
$142,924
Indirect Cost
$11,220
Name
University of Pittsburgh
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Feng, Haizhong; Lopez, Giselle Y; Kim, Chung Kwon et al. (2014) EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. J Clin Invest 124:3741-56
Lui, Vivian W Y; Hedberg, Matthew L; Li, Hua et al. (2013) Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Cancer Discov 3:761-9
McCall, Andrew A; Moy, Jennifer D; Puterbaugh, Sonya R et al. (2013) Responses of vestibular nucleus neurons to inputs from the hindlimb are enhanced following a bilateral labyrinthectomy. J Appl Physiol (1985) 114:742-51
Vaezi, Alec; Wang, Xiaozhe; Buch, Shama et al. (2011) XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck. Clin Cancer Res 17:5513-22
Cassell, Andre; Grandis, Jennifer R (2010) Investigational EGFR-targeted therapy in head and neck squamous cell carcinoma. Expert Opin Investig Drugs 19:709-22
Lai, Stephen Y; Childs, Erin E; Xi, Sichuan et al. (2005) Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma. Oncogene 24:4442-9