Research training for medical students, resident physicians, and post-residency fellows is essential to developing the next generation of clinician-scientists. Physicians clinically trained in otolaryngology-head and neck surgery are those most likely to undertake research in the NIDCD mission areas of hearing, taste, smell, voice, communication disorders, neuroscience, and related cellular biology. The goals of this application are to: 1) provide short-term (3 month) introductory research experiences to medical students to encourage them to seek careers in the communication sciences;2) to provide longer term (1 year) research experiences to medical students interested in otolaryngology, to encourage pursuit of residencies that include research training and, ultimately, academic careers;3) provide 18 months of research training to one otolaryngology resident/year, to define and develop research to be continued as an academic faculty member, complemented by a structured didactic program in Clinical Research Design and Statistical Analysis for trainees interested in clinical research;and 5) provide 1 year post-residency fellowships for 2 trainees/year to complement their clinical subspecialty training. The opportunity to attend extramural or intramural conferences or educational courses relevant to the trainee's chosen research discipline will be provided. Preceptors have been selected from our internationally-recognized faculty consisting of both basic and clinical researchers in a broad variety of disciplines. Many faculty preceptors are themselves accomplished clinician-scientists who are in demand as research mentors. Major focuses of research include the molecular genetics of hearing loss, neural mechanisms of auditory processing, tissue bioengineering, the molecular biology of neural regeneration, and head and neck oncology. The research programs and facilities of the Department of Otolaryngology-Head and Neck Surgery and the Kresge Hearing Research Institute are among the best in the world and represent a major strength. The Multidisciplinary Clinical Researchers in Training Program (MCRiT), funded by a recent Roadmap T32, provides a unique and outstanding didactic and practical program in clinical research. In addition, the University of Michigan has extensive investments in both clinical and basic research in terms of the pending Clinical Translational Science Award, numerous core facilities, and major cross-departmental centers.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
5T32DC005356-09
Application #
7837693
Study Section
Special Emphasis Panel (ZDC1-SRB-O (11))
Program Officer
Sklare, Dan
Project Start
2002-07-01
Project End
2012-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
9
Fiscal Year
2010
Total Cost
$313,641
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Birkeland, Andrew C; Rosko, Andrew J; Beesley, Lauren et al. (2017) Preoperative Tracheostomy Is Associated with Poor Disease-Free Survival in Recurrent Laryngeal Cancer. Otolaryngol Head Neck Surg 157:432-438
Birkeland, Andrew C; Beesley, Lauren; Bellile, Emily et al. (2017) Predictors of survival after total laryngectomy for recurrent/persistent laryngeal squamous cell carcinoma. Head Neck 39:2512-2518
Yousif, Jenna; Birkeland, Andrew C; Spector, Matthew E (2017) A Young Man With Hypercalcemia. JAMA Otolaryngol Head Neck Surg 143:311-312
Hoesli, Rebecca C; Orringer, Daniel A; McHugh, Jonathan B et al. (2017) Coherent Raman Scattering Microscopy for Evaluation of Head and Neck Carcinoma. Otolaryngol Head Neck Surg 157:448-453
Kovatch, K J; Hoban, C W; Shuman, A G (2017) Thyroid cancer surgery guidelines in an era of de-escalation. Eur J Surg Oncol :
Rosko, Andrew; Birkeland, Andrew; Shuman, Andrew et al. (2017) Positron emission tomography-CT prediction of occult nodal metastasis in recurrent laryngeal cancer. Head Neck 39:980-987
Matovina, Chloe; Birkeland, Andrew C; Zick, Suzanna et al. (2017) Integrative Medicine in Head and Neck Cancer. Otolaryngol Head Neck Surg 156:228-237
Mann, J E; Hoesli, R; Michmerhuizen, N L et al. (2017) Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC. J Cancer 8:332-344
Ha, Jennifer F; Morrison, Robert J; Green, Glenn E et al. (2017) Computer-Aided Design and 3-Dimensional Printing for Costal Cartilage Simulation of Airway Graft Carving. Otolaryngol Head Neck Surg 156:1044-1047
Birkeland, Andrew C; Burgin, Sarah J; Yanik, Megan et al. (2017) Pathogenetic Analysis of Sinonasal Teratocarcinosarcomas Reveal Actionable ?-catenin Overexpression and a ?-catenin Mutation. J Neurol Surg B Skull Base 78:346-352

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