This grant application is aligned with the NIH Blueprint for Neuroscience Research which highlights the need to accelerate the pace of discovery in neuroscience research and to translate new discoveries into clinical interventions that will reduce the public health burden of the chronic consequencce of nervous system disorders. Across the nation there is a shortage of scientists who can translate discoveries from molecular, cellular and systems neuroscience into diagnostic tests/markers and strategies for treatment of disorders affecting the nervous system in general and communication and swallow functional systems in particular. Rapid translation of promising interventions from animal models to clinical trials will require the concomitant training of academic clinicians and basic scientists who are capable of promoting this scientific synergy by bridging the two fields in order to address disorders of a complex nervous system that affect communication and swallowing functions. The University of Florida has established a priority in rehabilitation research targeting neurologically induced communication disorders of adults as well as experiential and molecular influences on neuroplasticity. To fulfill the need for trained scientists in this area, the purpose of this application is to develop and implement at the University of Florida a comprehensive, integrated postdoctoral training program that focuses on fundamental pathobiological mechanisms, clinical ramifications, as well as critical features of research design that facilitate the discovery-to-treatment process. The broad, long term objective is to increase the number of highly trained basic and applied scientists prepared to participate in translational research targeting the treatment of communication and swallow disorders resulting from diseases or injury to the nervous system.
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| Falchook, Adam D; Burtis, D Brandon; Acosta, Lealani M et al. (2014) Praxis and writing in a right-hander with crossed aphasia. Neurocase 20:317-27 |
| Nocera, Joe R; Roemmich, Ryan; Elrod, Jonathan et al. (2013) Effects of cognitive task on gait initiation in Parkinson disease: evidence of motor prioritization? J Rehabil Res Dev 50:699-708 |
| Burtis, D Brandon; Williamson, John B; Mishra, Monika et al. (2013) The blindside: impact of monocular occlusion on spatial attention. J Clin Exp Neuropsychol 35:291-7 |
| Falchook, Adam D; Mayberry, Rachel I; Poizner, Howard et al. (2013) Sign language aphasia from a neurodegenerative disease. Neurocase 19:434-44 |
| Meinzer, Marcus; Rodriguez, Amy D; Gonzalez Rothi, Leslie J (2012) First decade of research on constrained-induced treatment approaches for aphasia rehabilitation. Arch Phys Med Rehabil 93:S35-45 |
| Meinzer, Marcus; Seeds, Lauren; Flaisch, Tobias et al. (2012) Impact of changed positive and negative task-related brain activity on word-retrieval in aging. Neurobiol Aging 33:656-69 |
| Wheeler-Hegland, Karen; Pitts, Teresa; Davenport, Paul W (2011) Peak morphology and scalp topography of the pharyngeal sensory-evoked potential. Dysphagia 26:287-94 |
| Meinzer, Marcus; Breitenstein, Caterina; Westerhoff, Ursula et al. (2011) Motor cortex preactivation by standing facilitates word retrieval in aphasia. Neurorehabil Neural Repair 25:178-87 |
| Nocera, Joe R; Horvat, Michael; Ray, Christopher T (2010) Impaired step up/over in persons with Parkinson's disease. Adapt Phys Activ Q 27:87-95 |
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