The University of Southern California Neuroscience Graduate Program (DSC NGP) and the House Ear Institute (HEI) together propose to establish a unique research training program for predoctoral, postdoctoral, and postgraduate physician-scientist scholars: the USC/HEI Hearing and Communication Neuroscience Training Program. The program brings together a broad spectrum of scientists to enhance inter-disciplinary communication, and offers the unique advantage of providing research training opportunities that bridge basic science with clinical hearing and communications applications. The program will further solidify the research and training interactions between scientists in the College of Letters Arts &Sciences, the Keck School of Medicine, the Viterbi School of Engineering at DSC, and HEI. The program will combine the strengths of an outstanding group of researchers focused on basic aspects of hearing and communication, the resources of the USC Graduate Program in Neuroscience and the HEI,and the expertise in clinical otologic excellence of the HEI. The rationale of this proposal is to engage predoctoral, postdoctoral, and physician-scientist trainees in a highly interactive and multidisciplinary training experience ranging from cell biology to cognitive neuroscience and linguistics that is unfettered by conventional departmental barriers, and actively facilitates their development as independent scientists. We propose four predoctoral and two postdoctoral scholars per year for a maximum of two years support for any one scholar. One of the postdoctoral scholars can be a physician-scientist recruited from the HEI Clinical Research Fellowship or the USC Otolaryngology Residency Program. Pre-doctoral trainees will typically join the program during the second year of their graduate training, whereas the level of seniority of post-doctoral trainees participating in the program will vary. All trainees will receive training in all aspects of hearing- and communication-related research and practical skills that will prepare them for careers in independently-funded research, education, and industry. The ability to expose trainees directly to both cutting-edge research in basic science as well as ongoing clinical research and applications is a major and unique strength of the program.
This proposal focuses on research and training that are directly relevant to speech and language disorders and communication disabilities in humans. This training program will help prepare a cadre of scientists to address fundamental questions pertaining to hearing and vocal communication. These individuals will not only advance our understanding of biologic and behavioral bases of a broad spectrum of auditory-vocal communication disorders, but will also generate innovative diagnostic and therapeutic applications.
|Shi, Yingxiao; Lin, Shaoyu; Staats, Kim A et al. (2018) Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nat Med 24:313-325|
|Gnedeva, Ksenia; Hudspeth, A J; Segil, Neil (2018) Three-dimensional Organotypic Cultures of Vestibular and Auditory Sensory Organs. J Vis Exp :|
|Lin, Candise Y; Wang, Min; Newman, Rochelle S et al. (2018) The development of stress sensitivity and its contribution to word reading in school-aged children. J Res Read 41:259-277|
|Li, Chuchu; Wang, Min; Lin, Candise Y (2017) Recent language experience influences cross-language activation in bilinguals with different scripts. Int J Billing 21:500-517|
|Smeeton, Joanna; Askary, Amjad; Crump, J Gage (2017) Building and maintaining joints by exquisite local control of cell fate. Wiley Interdiscip Rev Dev Biol 6:|
|Stelmach, Julia; Landsberger, David M; Padilla, Monica et al. (2017) Determining the minimum number of electrodes that need to be pitch matched to accurately estimate pitch matches across the array. Int J Audiol 56:894-899|
|Achiro, Jennifer M; Shen, John; Bottjer, Sarah W (2017) Neural activity in cortico-basal ganglia circuits of juvenile songbirds encodes performance during goal-directed learning. Elife 6:|
|Gnedeva, Ksenia; Jacobo, Adrian; Salvi, Joshua D et al. (2017) Elastic force restricts growth of the murine utricle. Elife 6:|
|Askary, Amjad; Xu, Pengfei; Barske, Lindsey et al. (2017) Genome-wide analysis of facial skeletal regionalization in zebrafish. Development 144:2994-3005|
|Töger, Johannes; Sorensen, Tanner; Somandepalli, Krishna et al. (2017) Test-retest repeatability of human speech biomarkers from static and real-time dynamic magnetic resonance imaging. J Acoust Soc Am 141:3323|
Showing the most recent 10 out of 43 publications