The University of Southern California (USC) and the House Research Institute (HRI) together have established a research training program for predoctoral, postdoctoral, and physician-scientist scholars: the USC/HRI Hearing and Communication Neuroscience (HCN) Training Program. The program brings together a broad spectrum of scientists to enhance inter-disciplinary communication, and offers the advantage of providing research training opportunities that bridge basic science with translational research and clinical hearing applications. The program serves to reinforce research and training interactions between scientists at HRI with scientists in the Dornsife College of Letters Arts & Sciences, the Keck School of Medicine, and the Viterbi School of Engineering at USC. The program combines the strengths of an outstanding group of researchers focused on basic aspects of hearing and vocal communication at both USC and HRI, the resources of USC graduate programs in Neuroscience, Psychology, and Linguistics, and the expertise in clinical otologic excellence of HRI. The rationale of this proposal is to engage predoctoral, postdoctoral, and physician- scientist trainees in a highly interactive and multi-disciplinary training experienc ranging from cell biology to cognitive neuroscience and linguistics that is unfettered by conventional departmental barriers, and actively facilitates their development as independent scientists. We have successfully filled all positions with predoctoral and postdoctoral scholars every year during the first four years of the grant. One of the postdoctoral scholars was a physician-scientist who also completed the House Neurotology Clinical Fellowship Program. Predoctoral trainees typically join the program during the second year of their graduate training, whereas the level of seniority of post-doctoral trainees participating in the program varies. All trainees receive multi-disciplinary training in all aspects of hearing and communication neuroscience, as well as practical skills that will prepare them for careers in independently-funded research, education, and industry. The ability to expose trainees directly to both cutting-edge research in basic science as well as ongoing clinical research and applications is a major strength of the program.

Public Health Relevance

This proposal focuses on research and training that are directly relevant to neural mechanisms of speech and language disorders and communication disabilities in humans. This training program will help prepare a cadre of scientists to address fundamental questions pertaining to hearing and vocal communication. These young scientists will not only advance our understanding of neural bases of a broad spectrum of auditory-vocal communication disorders, but will also generate innovative diagnostic and therapeutic applications.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Institutional National Research Service Award (T32)
Project #
5T32DC009975-07
Application #
8828164
Study Section
Special Emphasis Panel (ZDC1)
Program Officer
Rivera-Rentas, Alberto L
Project Start
2009-07-01
Project End
2019-06-30
Budget Start
2015-07-01
Budget End
2016-06-30
Support Year
7
Fiscal Year
2015
Total Cost
Indirect Cost
Name
University of Southern California
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90032
Shi, Yingxiao; Lin, Shaoyu; Staats, Kim A et al. (2018) Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nat Med 24:313-325
Gnedeva, Ksenia; Hudspeth, A J; Segil, Neil (2018) Three-dimensional Organotypic Cultures of Vestibular and Auditory Sensory Organs. J Vis Exp :
Lin, Candise Y; Wang, Min; Newman, Rochelle S et al. (2018) The development of stress sensitivity and its contribution to word reading in school-aged children. J Res Read 41:259-277
Gnedeva, Ksenia; Jacobo, Adrian; Salvi, Joshua D et al. (2017) Elastic force restricts growth of the murine utricle. Elife 6:
Askary, Amjad; Xu, Pengfei; Barske, Lindsey et al. (2017) Genome-wide analysis of facial skeletal regionalization in zebrafish. Development 144:2994-3005
Töger, Johannes; Sorensen, Tanner; Somandepalli, Krishna et al. (2017) Test-retest repeatability of human speech biomarkers from static and real-time dynamic magnetic resonance imaging. J Acoust Soc Am 141:3323
Paterson, Amy K; Bottjer, Sarah W (2017) Cortical inter-hemispheric circuits for multimodal vocal learning in songbirds. J Comp Neurol 525:3312-3340
Li, Chuchu; Wang, Min; Lin, Candise Y (2017) Recent language experience influences cross-language activation in bilinguals with different scripts. Int J Billing 21:500-517
Smeeton, Joanna; Askary, Amjad; Crump, J Gage (2017) Building and maintaining joints by exquisite local control of cell fate. Wiley Interdiscip Rev Dev Biol 6:
Stelmach, Julia; Landsberger, David M; Padilla, Monica et al. (2017) Determining the minimum number of electrodes that need to be pitch matched to accurately estimate pitch matches across the array. Int J Audiol 56:894-899

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