The goal of this application is to obtain support for our long-standing and extremely successful training program in oral health research. We will take advantage of new opportunities to strengthen our tradition of training promising scientists to become leaders as research faculty in the nation's dental, medical, and health-related research institutions. The proposed program will foster interdisciplinary training opportunities in both basc and translational research that address oral health and diseases in order to produce a cadre of well-trained and eventually independent investigators. This application promotes continuing collaboration between several units within UB, including the Schools of Dental Medicine, Medicine and Biomedical Sciences, Engineering and Applied Sciences, and Public Health and Health Professions, the Buffalo Center for Ontological Research, and the Roswell Park Cancer Institute (RPCI). Also, the Center for Excellence in Bioinformatics and Life Sciences (COEBLS) at UB has taken a prominent role in providing interesting and novel research opportunities for our trainees. The organization and requirements of the program center on oral health research, yet take advantage of the numerous other interdisciplinary and cross-training opportunities available. This program will support two training pathways:
Aim 1. Doctoral (PhD) training for dentist and non-dentist trainees Aim 2. Post-Doctoral training for DDS and/or PhD fellows to develop as independent investigators in dental, oral, and craniofacial research The organization and requirements of the program center on oral health research, yet take advantage of numerous interdisciplinary, interprofessional, and cross-training opportunities. Implementing these aims will benefit trainees, investigators, and research staff across a broad range of disciplines and levels of training.
The Oral Biology graduate program at the School of Dental Medicine at the University at Buffalo offers a wide range of research-intensive interdisciplinary graduate and post-doctoral programs aimed at creating the next generation of dental and craniofacial health professionals. The purpose of this project is to attract new pre-doctoral and post-doctoral trainees into dental research careers - especially those talented students who may not have considered oral health research as a career path. This proposal requests institutional support for both our PhD program to train dentists (post-doctoral) and non-dentists (pre-doctoral), and for our post-doctoral program to train non-clinician PhD fellows.
|Varanat, M; Haase, E M; Kay, J G et al. (2016) Activation of the TREM-1 pathway in human monocytes by periodontal pathogens and oral commensal bacteria. Mol Oral Microbiol :|
|Akinkugbe, A A; Sharma, S; Ohrbach, R et al. (2016) Directed Acyclic Graphs for Oral Disease Research. J Dent Res 95:853-9|
|Salvatori, O; Puri, S; Tati, S et al. (2016) Innate Immunity and Saliva in Candida albicans-mediated Oral Diseases. J Dent Res 95:365-71|
|Rabadi, Seham M; Sanchez, Belkys C; Varanat, Mrudula et al. (2016) Antioxidant Defenses of Francisella tularensis Modulate Macrophage Function and Production of Proinflammatory Cytokines. J Biol Chem 291:5009-21|
|Honma, Kiyonobu; Ruscitto, Angela; Frey, Andrew M et al. (2016) Sialic acid transporter NanT participates in Tannerella forsythia biofilm formation and survival on epithelial cells. Microb Pathog 94:12-20|
|Ruscitto, Angela; Hottmann, Isabel; Stafford, Graham P et al. (2016) Identification of a Novel N-Acetylmuramic Acid Transporter in Tannerella forsythia. J Bacteriol 198:3119-3125|
|Rizzo, J M; Oyelakin, A; Min, S et al. (2016) Î”Np63 regulates IL-33 and IL-31 signaling in atopic dermatitis. Cell Death Differ 23:1073-85|
|Li, Rui; Puri, Sumant; Tati, Swetha et al. (2015) Candida albicans Cek1 mitogen-activated protein kinase signaling enhances fungicidal activity of salivary histatin 5. Antimicrob Agents Chemother 59:3460-8|
|Puri, S; Li, R; Ruszaj, D et al. (2015) Iron binding modulates candidacidal properties of salivary histatin 5. J Dent Res 94:201-8|
|McCall, Andrew D; Baker, Olga J (2015) Characterization of Angiogenesis and Lymphangiogenesis in Human Minor Salivary Glands with SjÃ¶gren's Syndrome. J Histochem Cytochem 63:340-9|
Showing the most recent 10 out of 20 publications