The postdoctoral research training program in Endocrinology and Diabetes at the Massachusetts General Hospital provides intensive research experience in basic or clinical investigation, complemented by a didactic component appropriate to the training goals. The trainees are primarily M.D.'s and M.D./Ph.D.'s who desire a career in investigative endocrinology and academic medicine, as well as Ph.D.'s who want further research training. The trainees are selected from a large applicant pool on the basis of prior academic and/or research achievement, and evidence of strong commitment to a career in biomedical investigation. The Program director (J. Avruch) is a senior academician and endocrine investigator who governs in conjunction with a committee of experienced endocrine scientists (Habener, Kronenberg, Crowley, Neer, Freeman, Grinspoon and Klibanski). The faculty consists of 49 active, well-funded scientists, whose interests range broadly across the subdisciplines of endocrinology, and from clinical, bedside investigation to molecular mechanisms. The trainees are supervised closely by a primary faculty mentor, and interact extensively with junior faculty, who often serve as secondary mentors. An extensive program of didactic sessions complements the research activity. The training period is 2-3 years but may include several years additional experience at junior faculty status, so as to permit consolidation of skills and maximal competitiveness for independent support. The productivity of past trainees during training has been very high overall, as judged by the number and quality of trainee publications. The majority of program graduates remain in academia and a substantial number are in the biotechnology/pharmaceutical industry. Among those in academia, about one fifth of graduates since 1999 have an RO-1 and about two fifths have achieved transitional independent support, a usual precursor to RO-1 support. The facilities at the MGH are extensive, including an Institutional Clinical Research Support Program and over 50,000 square feet of modern laboratories dedicated to endocrine training faculty. This training grant is the central stabilizing financial element in this program, and is especially critical in enabling M.D. trainees to achieve careers in biomedical investigation.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007028-40
Application #
8695324
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
1975-07-01
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
40
Fiscal Year
2014
Total Cost
$651,745
Indirect Cost
$49,450
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Roszko, Kelly L; Bi, Ruiye; Gorvin, Caroline M et al. (2017) Knockin mouse with mutant G?11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors. JCI Insight 2:e91079
El-Khatib, Firas H; Balliro, Courtney; Hillard, Mallory A et al. (2017) Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial. Lancet 389:369-380
Tangren, Jessica Sheehan; Powe, Camille E; Ankers, Elizabeth et al. (2017) Pregnancy Outcomes after Clinical Recovery from AKI. J Am Soc Nephrol 28:1566-1574
Zanni, Markella V; Toribio, Mabel; Wilks, Moses Q et al. (2017) Application of a Novel CD206+ Macrophage-Specific Arterial Imaging Strategy in HIV-Infected Individuals. J Infect Dis 215:1264-1269
Dichtel, Laura E; Lawson, Elizabeth A; Schorr, Melanie et al. (2017) Neuroactive Steroids and Affective Symptoms in Women Across the Weight Spectrum. Neuropsychopharmacology :
Bachmann, Katherine N; Schorr, Melanie; Bruno, Alexander G et al. (2017) Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia Nervosa. J Clin Endocrinol Metab 102:57-68
Billings, Liana K; Jablonski, Kathleen A; Warner, A Sofia et al. (2017) Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention. J Clin Endocrinol Metab 102:2678-2689
Zanni, Markella V; Stone, Lauren A; Toribio, Mabel et al. (2017) Proprotein Convertase Subtilisin/Kexin 9 Levels in Relation to Systemic Immune Activation and Subclinical Coronary Plaque in HIV. Open Forum Infect Dis 4:ofx227
Schorr, Melanie; Thomas, Jennifer J; Eddy, Kamryn T et al. (2017) Bone density, body composition, and psychopathology of anorexia nervosa spectrum disorders in DSM-IV vs DSM-5. Int J Eat Disord 50:343-351
Ekhlaspour, Laya; Mondesir, Debbie; Lautsch, Norman et al. (2017) Comparative Accuracy of 17 Point-of-Care Glucose Meters. J Diabetes Sci Technol 11:558-566

Showing the most recent 10 out of 153 publications