This program started over 20 years ago under the leadership of Dr. Sanford B. Kranz, Professor of Medicine and Chief of Medical Hematology at Vanderbilt University. The purpose of the program is to provide postdoctoral research training in hematology for individuals with the M.D. or Ph.D. degree. In the present application, there are 16 participating faculty in the program. Most have primary appointments in the Departments of Medicine or Pathology, but there also are a number of basic science faculty who are interested in collaborative training with hematology group.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (SRC)
Program Officer
Bishop, Terry Rogers
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Vanderbilt University Medical Center
Internal Medicine/Medicine
Schools of Medicine
United States
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Dai, Chunhua; Chung, Ik-Joo; Krantz, Sanford B (2004) In human immature BFU-E tumor necrosis factor-alpha not only downregulates CDK6 but also directly produces apoptosis which is prevented by stem cell factor. Exp Hematol 32:911-7
Chung, Ik-Joo; Dai, Chunhua; Krantz, Sanford B (2003) Stem cell factor increases the expression of FLIP that inhibits IFNgamma -induced apoptosis in human erythroid progenitor cells. Blood 101:1324-8
Anderson, Patricia J; Bock, Paul E (2003) Role of prothrombin fragment 1 in the pathway of regulatory exosite I formation during conversion of human prothrombin to thrombin. J Biol Chem 278:44489-95
Dai, Chunhua; Chung, Ik-Joo; Jiang, Shazi et al. (2003) Reduction of cell cycle progression in human erythroid progenitor cells treated with tumour necrosis factor alpha occurs with reduced CDK6 and is partially reversed by CDK6 transduction. Br J Haematol 121:919-27
Anderson, Patricia J; Nesset, Anna; Bock, Paul E (2003) Effects of activation peptide bond cleavage and fragment 2 interactions on the pathway of exosite I expression during activation of human prethrombin 1 to thrombin. J Biol Chem 278:44482-8
Zhao, Runxiang; Guerrah, Abdelmadjid; Tang, Hua et al. (2002) Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling. J Biol Chem 277:7882-8
Qi, Ying; Zhao, Runxiang; Cao, Hongxi et al. (2002) Purification and characterization of protein tyrosine phosphatase PTP-MEG2. J Cell Biochem 86:79-89
Zhao, R; Qi, Y; Chen, J et al. (2001) FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphotidylinositol 3-phosphate. Exp Cell Res 265:329-38
Chen, J; Qi, Y; Zhao, R et al. (2001) Assay of protein tyrosine phosphatases by using matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Anal Biochem 292:51-8
Anderson, P J; Bock, P E (2001) Biotin derivatives of D-Phe-Pro-Arg-CH2Cl for active-site-specific labeling of thrombin and other serine proteinases. Anal Biochem 296:254-61

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