Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007318-18
Application #
2134839
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1978-09-15
Project End
1998-08-31
Budget Start
1995-09-01
Budget End
1996-08-31
Support Year
18
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
McGowan, Karen A; Nyhan, William L; Barshop, Bruce A et al. (2004) The role of methionine in ethylmalonic encephalopathy with petechiae. Arch Neurol 61:570-4
Campana, W M; O'Brien, J S; Hiraiwa, M et al. (1999) Secretion of prosaposin, a multifunctional protein, by breast cancer cells. Biochim Biophys Acta 1427:392-400
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Naviaux, R K; Nyhan, W L; Barshop, B A et al. (1999) Mitochondrial DNA polymerase gamma deficiency and mtDNA depletion in a child with Alpers' syndrome. Ann Neurol 45:54-8
Calcutt, N A; Campana, W M; Eskeland, N L et al. (1999) Prosaposin gene expression and the efficacy of a prosaposin-derived peptide in preventing structural and functional disorders of peripheral nerve in diabetic rats. J Neuropathol Exp Neurol 58:628-36
Campana, W M; Hiraiwa, M; O'Brien, J S (1998) Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells. FASEB J 12:307-14
Campana, W M; Misasi, R; O'Brien, J S (1998) Identification of a neurotrophic sequence in erythropoietin. Int J Mol Med 1:235-41
Campana, W M; Eskeland, N; Calcutt, N A et al. (1998) Prosaptide prevents paclitaxel neurotoxicity. Neurotoxicology 19:237-44
Hiraiwa, M; Campana, W M; Martin, B M et al. (1997) Prosaposin receptor: evidence for a G-protein-associated receptor. Biochem Biophys Res Commun 240:415-8
Hiraiwa, M; Taylor, E M; Campana, W M et al. (1997) Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides. Proc Natl Acad Sci U S A 94:4778-81

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