? This training program, which has been in continuous existence since 1975 as initially started with Dr. Trier, is designed to prepare physicians and selected postdoctoral scientists from allied fields for academic careers as independently funded investigators on the faculty of university-based medical centers in either basic or clinical research related to digestive diseases. Since 1999, this program has been led by Richard S. Blumberg (PI). This training program is closely integrated into the categorical Gastroenterology fellowship program at Brigham & Women's Hospital, which has two related tracks that reflect the major goals of the Institutional National Research Service Award (NRSA). These are a basic research track (3 trainees/year) and a clinical research track (2 trainees/year), both of which include a categorical year of clinical fellowship training in Gastroenterology funded by the institution and two years of research training supported by the Institutional NRSA for the development of physician-scientists and clinical investigators, respectively. Emphasis is placed on the recruitment of trainees with prior research experience (e.g. M.D., Ph.D. degrees). Both tracks continuously take advantage of the faculty and expertise of the Harvard Medical School and its affiliated institutions (Dana Farber Cancer Institute, Harvard School of Public Health, Harvard Medical School and Boston Veterans Administration Health Care System). The Program Director, Dr. Richard S. Blumberg and 25 current preceptors provide training in the following major areas related to digestive diseases research: 1) Immunology and (Drs. R. Blumberg, S. Colgan, C. Terhorst); 2) Genetics (Drs. R. Maas, D. Beier); 3) Cell and Molecular Physiology (Drs. R. Goyal, C. Serhan, D. Soybel. W. Lencer, T. Mitchison, T. Roberts); 4) Clinical Research and Epidemiology (Drs. J. Ayanian, F. Li, G. Colditz, S. Syngal, N. Grace, P. Banks, C. Earle, C. Fuchs, R. Burakoff); 5) Gl Motility and Biophysics (Drs. M. Carey, H. Mashimo); 6) Gastroenterology and Hepatology (Drs. J. Trier, D. Cohen, C. Ukomadu); and 7) Oncology (Drs. Z. Zhu, M. Exley, R. Shivdasani). The program is administered by a T32 Executive Committee that is composed of individuals whose interests reflect these areas (Drs. R. Blumberg [Immunology], M. Carey [Cell and Molecular Physiology], S. Syngal [Clinical Research], S. Colgan [Physiology], D. Cohen and C. Ukomadu [Hepatology], Z. Zhu [Oncology] and J. Trier (emeritus member) and which provides oversight for the recruitment, training and career development of trainees as well as evaluates the training program and facilitates in the decision-making process for program changes. The program provides support for coursework in basic science disciplines from the Harvard Medical School and formal training in public health and epidemiology through a Masters in Public Health degree from the Harvard School of Public Health. In addition, trainees have the opportunity to attend a Clinical Effectiveness program at the Harvard School of Public Health, a seven-week intensive program that provides the Epidemiology and Health Policy fundamentals attained typically from the Masters in Public Health. This program, with its long tradition, of training academic leaders, allows for broad training in the basic and clinical sciences. Thus allowing optimal development of the particular strengths and interests of individual trainees. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
2T32DK007533-21A1
Application #
7168694
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
Project Start
1985-07-01
Project End
2011-06-30
Budget Start
2006-09-01
Budget End
2007-06-30
Support Year
21
Fiscal Year
2006
Total Cost
$256,459
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Kim, Walter M; Kaser, Arthur; Blumberg, Richard S (2017) A role for oncostatin M in inflammatory bowel disease. Nat Med 23:535-536
Jirapinyo, Pichamol; Thompson, Christopher C (2017) Endoscopic Bariatric and Metabolic Therapies: Surgical Analogues and Mechanisms of Action. Clin Gastroenterol Hepatol 15:619-630
Schulman, Allison R; Ryou, Marvin; Aihara, Hiro et al. (2017) EUS-guided intrahepatic portosystemic shunt with direct portal pressure measurements: a novel alternative to transjugular intrahepatic portosystemic shunting. Gastrointest Endosc 85:243-247
Schulman, Allison R; Thompson, Christopher C (2017) Endoscopic reconstruction of Roux-en-Y gastric bypass with placement of gastrojejunal and remnant-jejunal lumen-apposing metal stents. Gastrointest Endosc :
Kumar, Nitin; Thompson, Christopher C (2017) Remnant gastropathy due to bile reflux after Roux-en-Y gastric bypass: a unique cause of abdominal pain and successful treatment with ursodiol. Surg Endosc 31:5399-5402
Barnes, Edward L; Nestor, Molly; Onyewadume, Louisa et al. (2017) High Dietary Intake of Specific Fatty Acids Increases Risk of Flares in Patients With Ulcerative Colitis in Remission During Treatment With Aminosalicylates. Clin Gastroenterol Hepatol 15:1390-1396.e1
Schulman, Allison R; Kumar, Nitin; Thompson, Christopher C (2017) Transoral outlet reduction: a comparison of purse-string with interrupted stitch technique. Gastrointest Endosc :
Schulman, Allison R; Thompson, Christopher C (2017) Utility of Bile Acid Scintigraphy in the Diagnosis of Remnant Gastropathy in Patients with Roux-en-Y Gastric Bypass. Obes Surg 27:2750-2753
Kumar, Nitin; Abu Dayyeh, Barham K; Lopez-Nava Breviere, Gontrand et al. (2017) Endoscopic sutured gastroplasty: procedure evolution from first-in-man cases through current technique. Surg Endosc :
Storm, Andrew C; Thompson, Christopher C (2017) Endoscopic Treatments Following Bariatric Surgery. Gastrointest Endosc Clin N Am 27:233-244

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