This training program, which has been in continuous existence since 1975 and initially started with Dr. Jerry Trier, is designed to prepare physicians and selected postdoctoral scientists from allied fields for academic careers as independently funded investigators on the faculty of university-based medical centers in either basic or clinical research related to digestive diseases. Since 1999, this program has been led by Dr. Richard S. Blumberg (PI); who incidentally was a trainee in this program (1987-1988). This training program is closely integrated into the categorical Gastroenterology fellowship program at The Brigham & Women's Hospital (BWH), which has two related tracks that reflect the major goals of the Institutional National Research Service Award (NRSA). These is a basic research track (1-2 trainees/year) and a clinical research track (2-3 trainees/year), both of which include a categorical year of clinical fellowship training in Gastroenterology funded by the institution and two years of research training supported by the Institutional NRSA for the development of physician-scientists and clinical investigators, respectively. Emphasis is placed on the recruitment of trainees with prior research experience (e.g. M.D., Ph.D. degrees). Both tracks continuously take advantage of the faculty and expertise of the Harvard Medical School (HMS) and its affiliated institutions (Dana Farber Cancer Institute, Harvard School of Public Health, Harvard Medical School, Massachusetts Institute of Technology and the Veterans Administration Boston Healthcare System). The Program Director, Dr. Richard S. Blumberg and 18 current preceptors provide training in the following major areas related to digestive diseases research: 1) Immunology and Microbiology (Drs. R. Blumberg); 2) Genetics (Drs. W. Goessling, J. Lieberman, R. Maas); 3) Cell and Molecular Physiology (Drs. R. Goyal, W. Lencer); 4) Clinical Research and Epidemiology (Drs. P. Banks, R. Burakoff, C. Fuchs, C. Thompson, S. Syngal); 5) GI Motility and Biophysics (Drs. H. Mashimo); 6) Hepatology and Lipid Biology (Drs. S. Bhatia, D. Cohen); 7) Oncology (Drs. M. Bertagnolli, R. Shivdasani, W. Goessling); and 8) Inflammatory Bowel Disease (IBD) (Drs. J Korzenik, S. Snapper). The program is administered by a T32 Executive Committee that is composed of individuals whose interests reflect these areas (Drs. R. Blumberg [Immunology], W. Lencer [Cell and Molecular Physiology], D. Cohen [Hepatology], S. Syngal [Clinical Research], C. Ukomadu [Minority Development; who is currently part-time faculty at BWH and HMS as he is Director of Innovation, Novartis Pharmaceuticals], W. Goessling [Oncology], and S. Snapper [IBD]), which provides oversight for the recruitment, training and career development of trainees as well as evaluates the training program and facilitates in the decision-making process for program changes. The program provides support for coursework in basic science disciplines from the Harvard Medical School and formal training in public health and epidemiology through a Masters in Public Health degree from the Harvard School of Public Health. In addition, trainees have the opportunity to attend the Clinical Effectiveness program at the Harvard School of Public Health, a seven-week intensive program that provides the Epidemiology and Health Policy fundamentals attained typically from the Masters in Public Health. This program, with its long tradition of training academic leaders, allows for broad training in the basic and clinical sciences, thus allowing optimal development of the particular strengths and interests of individual trainees.

Public Health Relevance

Since 1975, our T32 training program focuses on preparing young physicians and post-doctoral scientists for visionary and committed research careers in academic Gastroenterology and Hepatology. With the assistance of the T32 funding, we can provide four T32 trainees the opportunity to have a nearly full-time research experience with an assigned research mentor as well as the resources to obtain further research training through educational courses including the potential to acquire a Masters of Public Health degree through the Harvard School of Public Health. Our program strives to train the next generation of academic professionals in Gastroenterology and Hepatology for strong research careers with the ultimate aim to enhance the outcomes for patients with digestive diseases as well as the general population

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
2T32DK007533-31
Application #
9074214
Study Section
Kidney, Urologic and Hematologic Diseases D Subcommittee (DDK)
Program Officer
Densmore, Christine L
Project Start
1985-07-01
Project End
2021-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
31
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
Jirapinyo, Pichamol; Thompson, Andrew C; Kröner, Paul T et al. (2018) Metabolic Effect of Foregut Exclusion Demonstrated by the Impact of Gastrogastric Fistula on Recurrence of Diabetes. J Am Coll Surg 226:259-266.e1
Schulman, Allison R; Kumar, Nitin; Thompson, Christopher C (2018) Transoral outlet reduction: a comparison of purse-string with interrupted stitch technique. Gastrointest Endosc 87:1222-1228
Schulman, Allison R; Thompson, Christopher C (2018) Endoscopic reconstruction of Roux-en-Y gastric bypass with placement of gastrojejunal and remnant-jejunal lumen-apposing metal stents. Gastrointest Endosc 87:890-891
Kumar, Nitin; Abu Dayyeh, Barham K; Lopez-Nava Breviere, Gontrand et al. (2018) Endoscopic sutured gastroplasty: procedure evolution from first-in-man cases through current technique. Surg Endosc 32:2159-2164
Jin, David X; Lacson, Ronilda; Cochon, Laila R et al. (2018) A Clinical Model for the Early Diagnosis of Acute Pancreatitis in the Emergency Department. Pancreas 47:871-879
Winter, R W; Collins, E; Cao, B et al. (2017) Higher 25-hydroxyvitamin D levels are associated with greater odds of remission with anti-tumour necrosis factor-? medications among patients with inflammatory bowel diseases. Aliment Pharmacol Ther 45:653-659
Schulman, Allison R; Popov, Violeta; Thompson, Christopher C (2017) Randomized sham-controlled trials in endoscopy: a systematic review and meta-analysis of adverse events. Gastrointest Endosc 86:972-985.e3
Storm, Andrew C; Thompson, Christopher C (2017) Endoscopic Treatments Following Bariatric Surgery. Gastrointest Endosc Clin N Am 27:233-244
Kim, Walter M; Kaser, Arthur; Blumberg, Richard S (2017) A role for oncostatin M in inflammatory bowel disease. Nat Med 23:535-536
Jirapinyo, Pichamol; Thompson, Christopher C (2017) Endoscopic Bariatric and Metabolic Therapies: Surgical Analogues and Mechanisms of Action. Clin Gastroenterol Hepatol 15:619-630

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