The increasing incidence of kidney disease in the U.S. and worldwide represents a major challenge to our health systems. There is a growing urgency to train physician scientists and Ph.D. scientists who can increase our understanding of disease pathogenesis and develop, implement and assess new therapeutic modalities to combat renal disease. The goal of the Vanderbilt Nephrology Training Program is to provide promising M.D. and/or Ph.D. postdoctoral fellows with the knowledge and the tools to become the leaders in both basic and translational research efforts to generate new understanding in the pathogenesis of kidney diseases and to develop and implement new treatments and cures for our patients with kidney disease. The faculty who participate in the Vanderbilt Nephrology Training Program represent a group of talented and accomplished researchers with a broad range of scientific expertise and research interests. This group consists of 25 investigators whose primary appointment is in either Adult or Pediatric Nephrology and 27 other clinical and basic scientists who have ongoing interests in kidney disease or associated scientific questions. The training faculty are based in 10 departments: Medicine, Pediatrics, Pathology, Cancer Biology, Surgery, Cell Biology, Biochemistry, Anesthesia and Biostatistics. Research interests of the primary faculty include mechanisms of chronic glomerular and tubulointerstitial injury, acute kidney injury, cell-matrix and cell-cell interactions, renal development, epithelial cell biology, eicosanoid biology, epidemiology of progressive kidney disease, development of clinical biomarkers, health services research and clinical trials. Our training program is structured to provide physician/scientist (M.D. or M.D/Ph.D.) and selected basic scientist (Ph.D) trainees with a focused and productive research experience that will serve as the foundation for an independent investigative career directed toward understanding and treatment of renal disease. Research opportunities for training in kidney disease have greatly expanded at Vanderbilt both within and outside of the Nephrology Division since the previous submission of this training program. In the present application, we are therefore requesting an increase in support from three to five postdoctoral trainees per year.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZDK1-GRB-G (J2))
Program Officer
Rys-Sikora, Krystyna E
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Vanderbilt University Medical Center
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Parr, Sharidan K; Clark, Amanda J; Bian, Aihua et al. (2015) Urinary L-FABP predicts poor outcomes in critically ill patients with early acute kidney injury. Kidney Int 87:640-8
Denny, Gerald B; Golper, Thomas A (2014) Does hemodialyzer reuse have a place in current ESRD care: "to be or not to be?". Semin Dial 27:256-8
Allen, Ryan M; Vickers, Kasey C (2014) Coenzyme Q10 increases cholesterol efflux and inhibits atherosclerosis through microRNAs. Arterioscler Thromb Vasc Biol 34:1795-7
Golper, Thomas A; Fissell, Rachel; Fissell, William H et al. (2014) Hemodialysis: core curriculum 2014. Am J Kidney Dis 63:153-63
Alves, Tahira P; Wu, Pingsheng; Ikizler, T Alp et al. (2013) Chronic kidney disease at presentation is not an independent risk factor for AIDS-defining events or death in HIV-infected persons. Clin Nephrol 79:93-100
Wright Nunes, Julie; Greene, Jane H; Wallston, Kenneth et al. (2013) Pilot study of a physician-delivered education tool to increase patient knowledge about CKD. Am J Kidney Dis 62:23-32
Maripuri, Saugar; Ikizler, T Alp; Cavanaugh, Kerri L (2013) Prevalence of pre-end-stage renal disease care and associated outcomes among urban, micropolitan, and rural dialysis patients. Am J Nephrol 37:274-80
Smith, James P; Haddad, Elias V; Taylor, Mary B et al. (2012) Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome. Hypertension 59:719-25
Maripuri, Saugar; Penson, David F; Ikizler, T Alp et al. (2011) Outpatient versus inpatient observation after percutaneous native kidney biopsy: a cost minimization study. Am J Nephrol 34:64-70
Wright Nunes, Julie A; Wallston, Kenneth A; Eden, Svetlana K et al. (2011) Associations among perceived and objective disease knowledge and satisfaction with physician communication in patients with chronic kidney disease. Kidney Int 80:1344-51

Showing the most recent 10 out of 24 publications