The primary focus of our training program continues to be to provide intensive and interdisciplinary basic science research training for a minimal period of two years for qualified individuals who are committed to pursuing a career in academic surgery. The purpose of this training program is to provide these trainees with the basic science research skills necessary to become independent investigators in areas of gastrointestinal (Gl) endocrinology, inflammation and cancer when they assume faculty positions. In addition we are adding a new focus area on Gl epidemiology/outcomes research which is assuming a greater importance for future translational investigators. The training faculty is composed of both basic scientists and academic surgeons who are collegial, collaborative and multidisciplinary;each faculty preceptor is a recognized expert in his or her field and has a long record of research productivity in the training of young investigators from the United States and abroad. The diversity of our training program is further enhanced by the inclusion of junior investigators who will act as co-preceptors and further assist in the mentorship of our trainees. The breadth and depth of the research techniques available in the laboratories of the various faculty members allow the trainees to become familiar with and adept at the application of state-of-the-art techniques for the comprehensive study of Gl diseases. All of our trainees are mentored within the context of a multidisciplinary team comprised of clinician-scientists and basic science mentors. The diversity of the experience depends on the needs of the trainees and his or her research interest. In addition to an intensive research experience, the trainee also participates in formal courses in molecular biology, radiation safety and scientific ethics. New courses will be added in epidemiology, outcomes research and translational research. Furthermore, the trainees participate in regularly scheduled departmental seminars and lectures which include a basic science lecture, departmental Grand Rounds and seminars presented by other departments or centers. All of our trainees are required to complete coursework for a Master of Medical Science (MMS) degree, with some of our trainees going on to complete PhD requirements. The Gl research training program in the Department of Surgery at the University of Texas Medical Branch at Galveston has a greater than 35 year history of training surgeons in clinical and basic science investigation. We have demonstrated a strong record of research productivity and have provided a nurturing academic environment for these trainees. Our training program is specifically designed to focus on the research training of academic surgeons so that they will be prepared to become independent scientists and incorporate the new and state-of-the-art techniques learned during their training period into a successful academic career.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
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University of Texas Medical Br Galveston
Schools of Medicine
United States
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Tamirisa, Nina P; Sheffield, Kristin M; Parmar, Abhishek D et al. (2015) Surgeon and Facility Variation in the Use of Minimally Invasive Breast Biopsy in Texas. Ann Surg 262:171-8
Cooper, Amanda B; Parmar, Abhishek D; Riall, Taylor S et al. (2015) Does the use of neoadjuvant therapy for pancreatic adenocarcinoma increase postoperative morbidity and mortality rates? J Gastrointest Surg 19:80-6; discussion 86-7
Parmar, Abhishek D; Sheffield, Kristin M; Adhikari, Deepak et al. (2015) PREOP-Gallstones: A Prognostic Nomogram for the Management of Symptomatic Cholelithiasis in Older Patients. Ann Surg 261:1184-90
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Chen, Haijun; Mrazek, Amy A; Wang, Xiaofu et al. (2014) Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo. Bioorg Med Chem 22:3393-404
Parmar, Abhishek D; Vargas, Gabriela M; Tamirisa, Nina P et al. (2014) Trajectory of care and use of multimodality therapy in older patients with pancreatic adenocarcinoma. Surgery 156:280-9
Vargas, Gabriela M; Parmar, Abhishek D; Sheffield, Kristin M et al. (2014) Impact of liver-directed therapy in colorectal cancer liver metastases. J Surg Res 191:42-50
Vargas, Gabriela M; Sheffield, Kristin M; Parmar, Abhishek D et al. (2014) Trends in treatment and survival in older patients presenting with stage IV colorectal cancer. J Gastrointest Surg 18:369-77
Djukom, Clarisse; Porro, Laura J; Mrazek, Amy et al. (2014) Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression. Pancreas 43:88-92

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