EXCEED THE SPACE PROVIDED. The Gastroenterology Research Training Program at the University of North Carolina at Chapel Hill is designed to promote the development of promising MD and PhD postdoctoral fellows as independent investigators and future university faculty members who will investigate the pathogenesis of gastrointestinal and hepatic diseases. Training of the postdoctoral fellow is individualized,and the most important component is conducted by the trainee in the faculty mentor's laboratory. Additional training includes didactic courses, seminars and conferences, and seminars on responsible conduct of research. The training faculty consists of 18 funded investigators from 11 basic science and clinical departments at the University of North Carolina, who are all full-time members of the NIDDK- funded Center for Gastrointestinal Biology and Disease (CGIBD). These broadly based faculty have a documented history of close interactions promoting multidisciplinary research. The postdoctoral fellows benefit from the unique strengths of digestive disease research at the University of North Carolina, which include the CGIBD with its research cores, a research-oriented Pediatric Gastroenterology Division, a coordinated research training program, animal models of digestive diseases, outstanding programs in gastrointestinal epidemiology and biostatistics, a Gene Therapy Center, and a Center for Alcohol Studies. The training program is directed by Drs. David A. Brenner and R. Balfour Sartor with the assistance of three senior gastrointestinal researchers who constitute the Training Program Advisory Committee. The program recruits two new fellows each year for a total of four fellows from a pool of MD adult gastroenterology fellows, MD Pediatric gastroenterology fellows, and PhD postdoctoral fellows. For the MD fellows, this research training program follows the completion of subspecialty clinical training. The trainees receive two and usually more years of research training with external support sought for later years. This institutional training grant promotes intensive training in molecular techniques and basic pathophysiology in a stimulating diverse but integrated investigative environment leading to broadly trained independent investigators capable of adapting to the rapid advances in research. PERFORMANCE SITE ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007737-10
Application #
6930326
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Podskalny, Judith M,
Project Start
1996-08-01
Project End
2006-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
10
Fiscal Year
2005
Total Cost
$126,784
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Wang, Jeremy R; Holt, James; McMillan, Leonard et al. (2018) FMLRC: Hybrid long read error correction using an FM-index. BMC Bioinformatics 19:50
Bhatt, Aadra P; Gunasekara, Dulan B; Speer, Jennifer et al. (2018) Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells. ACS Infect Dis 4:46-52
Rogala, Allison R; Schoenborn, Alexi A; Fee, Brian E et al. (2018) Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice. Dis Model Mech 11:
Gracz, Adam D; Samsa, Leigh Ann; Fordham, Matthew J et al. (2018) Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates. Gastroenterology 155:1508-1523.e10
Yu, Ai-Ming; Ingelman-Sundberg, Magnus; Cherrington, Nathan J et al. (2017) Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21st International Symposium on Microsomes and Drug Oxidations (MDO). Acta Pharm Sin B 7:241-248
Carr, Jacquelyn S; King, Stephanie; Dekaney, Christopher M (2017) Depletion of enteric bacteria diminishes leukocyte infiltration following doxorubicin-induced small intestinal damage in mice. PLoS One 12:e0173429
Ziegler, Amanda; Fogle, Callie; Blikslager, Anthony (2017) Update on the use of cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs in horses. J Am Vet Med Assoc 250:1271-1274
Bhatt, Aadra P; Redinbo, Matthew R; Bultman, Scott J (2017) The role of the microbiome in cancer development and therapy. CA Cancer J Clin 67:326-344
Jorgensen, Ine; Rayamajhi, Manira; Miao, Edward A (2017) Programmed cell death as a defence against infection. Nat Rev Immunol 17:151-164
Wang, Jeremy R; Quach, Bryan; Furey, Terrence S (2017) Correcting nucleotide-specific biases in high-throughput sequencing data. BMC Bioinformatics 18:357

Showing the most recent 10 out of 73 publications