The Renal Epidemiology Training Program prepares trainees to design, conduct, and analyze independent research in the expansive field of kidney disease in collaboration with faculty in the UNC Kidney Center (UNCKC), the Department of Epidemiology and other UNC schools and departments. The UNCKC, whose director Dr. Ronald Falk reports directly to the CEO and Dean of the UNC Healthcare System, allows for an integrated approach to research and education. The UNCKC includes members in the Schools of Medicine, Public Health, Dentistry, Pharmacology, and the College of Arts and Sciences. In this over-arching structure, trainees have the opportunity to obtain their Masters of Public Health (MPH), PhD, or design and implement other structured training. Guidance is provided by mentoring teams comprised of faculty with expertise and established collaborative research interests across diverse areas of current interest in the realm of kidney research including epidemiology, immunology, genetics, pathology, pharmacology, health policy and more. Faculty have special expertise in systemic diseases that affect the kidney, including lupus, vasculitis, diabetes, and hypertension. Access to study populations is available through clinics and existing study databases, such as the Atherosclerosis Risk in Communities (ARIC) study and the Strong Heart Study. The academic curriculum is supplemented by a structured schedule of seminars, conferences, performance reviews and close interaction with faculty. Trainees are well-informed about the scope and impact of areas of research needed in the field of kidney disease, and work with faculty mentoring teams to review the literature, develop research initiatives, conduct and analyze data, and prepare abstracts, research presentations, manuscripts and grants. This program began in 1998 with one post-doctoral trainee and has expanded to three post-doctoral (one minority supplement for 2006-2008) and two pre-doctoral candidates. The post doctoral program includes both adult and pediatric trainees. Eight of 9 post-doctoral trainees and all 3 pre-doctoral candidates have degrees from prestigious U.S. universities. One of the post-doctoral and 2/3 of our pre-doctoral trainees are from underrepresented minorities. Six candidates have completed their training, with five now in faculty positions at excellent academic medical centers and one in industry. All trainees have published manuscripts or manuscripts underway for a total of 103 manuscripts.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007750-12
Application #
7781390
Study Section
Special Emphasis Panel (ZDK1-GRB-S (J3))
Program Officer
Rankin, Tracy L
Project Start
1999-03-01
Project End
2013-02-28
Budget Start
2010-03-01
Budget End
2011-02-28
Support Year
12
Fiscal Year
2010
Total Cost
$186,227
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Li, Xiaojuan; Kshirsagar, Abhijit V; Brookhart, M Alan (2017) Safety of intravenous iron in hemodialysis patients. Hemodial Int 21 Suppl 1:S93-S103
Jones, Britta E; Yang, Jiajin; Muthigi, Akhil et al. (2017) Gene-Specific DNA Methylation Changes Predict Remission in Patients with ANCA-Associated Vasculitis. J Am Soc Nephrol 28:1175-1187
Kahkoska, A R; Mayer-Davis, E J; Hood, K K et al. (2017) Behavioural implications of traditional treatment and closed-loop automated insulin delivery systems in Type 1 diabetes: applying a cognitive restraint theory framework. Diabet Med 34:1500-1507
Alan Brookhart, M; Li, Xiaojuan; Kshirsagar, Abhijit V (2017) What are the Considerations in Balancing Benefits and Risks in Iron Treatment?: Balancing Benefits and Safety with Intravenous Iron Treatment. Semin Dial 30:25-27
Hardy, Shakia T; Holliday, Katelyn M; Chakladar, Sujatro et al. (2017) Heterogeneity in Blood Pressure Transitions Over the Life Course: Age-Specific Emergence of Racial/Ethnic and Sex Disparities in the United States. JAMA Cardiol 2:653-661
Payan Schober, Fernanda; Jobson, Meghan A; Poulton, Caroline J et al. (2017) Clinical Features and Outcomes of a Racially Diverse Population with Fibrillary Glomerulonephritis. Am J Nephrol 45:248-256
Hu, Xiuli; Yu, Jicheng; Qian, Chenggen et al. (2017) H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery. ACS Nano 11:613-620
Yang, Jiajin; Ge, Heng; Poulton, Caroline J et al. (2016) Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Clin Epigenetics 8:85
Assimon, Magdalene M; Nguyen, Thuy; Katsanos, Suzanne L et al. (2016) Identification of volume overload hospitalizations among hemodialysis patients using administrative claims: a validation study. BMC Nephrol 17:173
Glenn, Dorey; Ocegueda, Sophie; Nazareth, Meaghan et al. (2016) The global pediatric nephrology workforce: a survey of the International Pediatric Nephrology Association. BMC Nephrol 17:83

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