The rapid changes that have occurred in Gl surgery over the past decade have created a unique opportunity for the creation of new knowledge, and yet our training programs have not appropriately adapted to this changing reality. This T32 Program has been designed to train the next generation of academic Gl surgeons through a continued focus in the basic science field and an expanded focus on clinical research and surgical innovation, two research fields that have thus far been lacking when it comes to scientific rigor. The enormous resources and talented personnel in the Harvard Medical School community have been leveraged to create a unique environment for the research training of our future academic Gl surgeons. First funded in 1997 as a collaboration between the Departments of Surgery at the Brigham and Women's Hospital and the former Beth Israel Hospital, this program has been expanded to include investigators from all three major adult teaching hospital affiliates of Harvard Medical School (BIDMC, BWH, MGH). It is clear that a major impediment to promoting and maintaining high quality Gl surgical research has been the "silo" effect, whereby investigators from various disciplines function as independent entities with little or no interaction. Accordingly, this T32 program will be comprised of three research tracks: (1) Basic Science, (2) Clinical Research/Outcomes and (3) Surgical Technology/Innovation. The Program has been designed to bring surgeon-scientists together from these three different investigative disciplines, establishing a unique environment for collaboration and interaction. The Training Program Executive Committee (Hodin, Soybel, Hasselgren) will oversee the selection of trainees, designation of preceptors, prescription of formal coursework, and participation in programs teaching ethics and the responsible conduct in research. The Program is open to surgical residents or fellows in accredited U.S. Residency Programs and a pro-active process is in place to seek applications from individuals belonging to under-represented minority groups. This T32 Program is therefore designed to provide intensive, coordinated research training with the goal of preparing individuals to become independently funded investigators in the field of alimentary tract surgery.
(Seeinstructions): A large number of gastrointestinal (Gl) diseases are best treated through surgery. It is therefore imperative that surgeons be appropriately trained to perform research that will advance our knowledge of Gl diseases. This Program is designed to provide superb training to young surgeons so that they are able to pursue careers that will focus on improving the life of patients suffering from Gl diseases.
|Hamarneh, Sulaiman R; Mohamed, Mussa M Rafat; Economopoulos, Konstantinos P et al. (2014) A novel approach to maintain gut mucosal integrity using an oral enzyme supplement. Ann Surg 260:706-14; discussion 714-5|
|Fallon, Erica M; Nazarian, Ara; Nehra, Deepika et al. (2014) The effect of docosahexaenoic acid on bone microstructure in young mice and bone fracture in neonates. J Surg Res 191:148-55|
|Decker, Marquita R; Dodgion, Christopher M; Kwok, Alvin C et al. (2014) Specialization and the current practices of general surgeons. J Am Coll Surg 218:8-15|
|Fallon, Erica M; Mitchell, Paul D; Nehra, Deepika et al. (2014) Neonates with short bowel syndrome: an optimistic future for parenteral nutrition independence. JAMA Surg 149:663-70|
|Vemula, Praveen Kumar; Kohler, Jonathan E; Blass, Amy et al. (2014) Self-assembled hydrogel fibers for sensing the multi-compartment intracellular milieu. Sci Rep 4:4466|
|Fallon, Erica M; Nehra, Deepika; Carlson, Sarah J et al. (2014) Evaluation of anastomotic strength and drug safety after short-term sunitinib administration in rabbits. J Surg Res 187:101-6|
|Nehra, Deepika; Pan, Amy H; Le, Hau D et al. (2014) Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target? J Surg Res 188:451-8|
|Hasson, Rian M; Briggs, Alexandra; Carothers, Adelaide M et al. (2014) Estrogen receptor * or * loss in the colon of Min/+ mice promotes crypt expansion and impairs TGF* and HNF3* signaling. Carcinogenesis 35:96-102|
|Nandivada, Prathima; Carlson, Sarah J; Chang, Melissa I et al. (2013) Treatment of parenteral nutrition-associated liver disease: the role of lipid emulsions. Adv Nutr 4:711-7|
|Nehs, Matthew A; Nucera, Carmelo; Nagarkatti, Sushruta S et al. (2012) Late intervention with anti-BRAF(V600E) therapy induces tumor regression in an orthotopic mouse model of human anaplastic thyroid cancer. Endocrinology 153:985-94|
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