This application is for renewal of the Ruth L. Kirschstein National Research Service Award Postdoctoral Research Training Program (T32) in Pediatric Gastroenterology, Hepatology and Nutrition at the University of California, San Francisco (UCSF). The Program aims to train talented and dedicated young physicians to become independent and productive scientific investigators. These future scientists will research important health problems, focusing on the causes, pathogenesis, and treatment of digestive, liver and nutritional disorders in infants and children. Preference is given to trainees committed to a 4- year training program, including 3 years of research training in either Basic or Clinical/Translational Research mentored by established scientists. Basic research experience is supplemented with coursework, seminars, and inter-departmental retreats;trainees in clinical research all participate in the well-established Training in Clinical Research Program that includes a 2-year Master's Degree in Clinical Research. Each trainee pursues an obligatory research project(s) supervised by experienced preceptors. Entry requirements include a MD degree and 3 years of residency in clinical pediatrics. Applicants with a PhD degree and defined career goals related to developmental gastroenterology or nutrition are also eligible. Administration of the program is restructured to take advantage of the strengthened Division of Pediatric Gastroenterology/Nutrition under the primary direction of Dr. Melvin Heyman and associate direction from Dr. Philip Rosenthal. The quality of educational and research programs and activities will be closely monitored by trainee mentors, research preceptors, Internal Advisors, the Associate Program Director, the Program Director, and periodic evaluations by External Advisors. An increase from 3 to 4 training positions is requested in Years 36-40.

Public Health Relevance

This Program is directly relevant to child health and development in training the next generation of scientists who will generate the advances essential for improving the quality of life and survival rates of children and adolescents with gastrointestinal, liver and nutrition-related disorders. Further, this training program represents n investment in the future of public health in general, as the multidisciplinary, intensive and innovative training provided by this Program will educate the leaders, teachers, and professional role models who will determine the direction and contributions of American medicine domestically and throughout the world, particularly as relates to pediatric gastroenterology, hepatology and nutrition.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
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University of California San Francisco
Schools of Medicine
San Francisco
United States
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Perito, Emily R; Phelps, Andrew; Vase, Tabitha et al. (2018) Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors. J Pediatr 193:119-127.e1
Verstraete, Sofia G; Wojcicki, Janet M; Perito, Emily R et al. (2018) Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010. Environ Health 17:12
Bayrer, James R; Wang, Hongtao; Nattiv, Roy et al. (2018) LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nat Commun 9:4055
Suh, Jung H; Degagné, Émilie; Gleghorn, Elizabeth E et al. (2018) Sphingosine-1-Phosphate Signaling and Metabolism Gene Signature in Pediatric Inflammatory Bowel Disease: A Matched-case Control Pilot Study. Inflamm Bowel Dis 24:1321-1334
Krams, S M; Schaffert, S; Lau, A H et al. (2017) Applying Mass Cytometry to the Analysis of Lymphoid Populations in Transplantation. Am J Transplant 17:1992-1999
Wojcicki, Janet M; de Schweinitz, Peter (2017) Store owners as potential agents of change: energy drinks in the interior of Alaska. Int J Circumpolar Health 76:1400362
Perito, Emily R; Ajmera, Veeral; Bass, Nathan M et al. (2017) Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. Hepatol Commun 1:609-622
Fox, Cade B; Nemeth, Cameron L; Chevalier, Rachel W et al. (2017) Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading. Bioeng Transl Med 2:9-16
Fernandes, Melissa A; Braun, Hillary J; Evason, Kim et al. (2017) De novo inflammatory bowel disease after pediatric kidney or liver transplant. Pediatr Transplant 21:
Perito, Emily R; Lustig, Robert H; Rosenthal, Philip (2017) Prediabetes in Pediatric Recipients of Liver Transplant: Mechanism and Risk Factors. J Pediatr 182:223-231.e3

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