This application is for renewal of the Ruth L. Kirschstein National Research Service Award Postdoctoral Research Training Program (T32) in Pediatric Gastroenterology, Hepatology and Nutrition at the University of California, San Francisco (UCSF). The Program aims to train talented and dedicated young physicians to become independent and productive scientific investigators. These future scientists will research important health problems, focusing on the causes, pathogenesis, and treatment of digestive, liver and nutritional disorders in infants and children. Preference is given to trainees committed to a 4- year training program, including 3 years of research training in either Basic or Clinical/Translational Research mentored by established scientists. Basic research experience is supplemented with coursework, seminars, and inter-departmental retreats;trainees in clinical research all participate in the well-established Training in Clinical Research Program that includes a 2-year Master's Degree in Clinical Research. Each trainee pursues an obligatory research project(s) supervised by experienced preceptors. Entry requirements include a MD degree and 3 years of residency in clinical pediatrics. Applicants with a PhD degree and defined career goals related to developmental gastroenterology or nutrition are also eligible. Administration of the program is restructured to take advantage of the strengthened Division of Pediatric Gastroenterology/Nutrition under the primary direction of Dr. Melvin Heyman and associate direction from Dr. Philip Rosenthal. The quality of educational and research programs and activities will be closely monitored by trainee mentors, research preceptors, Internal Advisors, the Associate Program Director, the Program Director, and periodic evaluations by External Advisors. An increase from 3 to 4 training positions is requested in Years 36-40.
This Program is directly relevant to child health and development in training the next generation of scientists who will generate the advances essential for improving the quality of life and survival rates of children and adolescents with gastrointestinal, liver and nutrition-related disorders. Further, this training program represents n investment in the future of public health in general, as the multidisciplinary, intensive and innovative training provided by this Program will educate the leaders, teachers, and professional role models who will determine the direction and contributions of American medicine domestically and throughout the world, particularly as relates to pediatric gastroenterology, hepatology and nutrition.
|Lowe, Margaret M; Mold, Jeff E; Kanwar, Bittoo et al. (2014) Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production. PLoS One 9:e87877|
|Reece, Jeanette C; Martyushev, Alexey; Petravic, Janka et al. (2014) Measuring turnover of SIV DNA in resting CD4+ T cells using pyrosequencing: implications for the timing of HIV eradication therapies. PLoS One 9:e93330|
|Salazar, Guadalupe; Heyman, Melvin B (2014) Benefits of attending a summer camp for children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 59:33-8|
|Perito, Emily R; Tsai, Patrika M; Hawley, Sarah et al. (2013) Targeted hepatic sonography during clinic visits for detection of fatty liver in overweight children: a pilot study. J Ultrasound Med 32:637-43|
|Salazar, Guadalupe; Barker, Judith C; Heyman, Melvin B (2013) Medical students' conceptualizations of quality of life associated with children with IBD. J Pediatr Gastroenterol Nutr 57:493-9|
|Pak, Seung; Holland, Nina; Garnett, Elizabeth A et al. (2012) Cytokine profiles in peripheral blood of children and adults with Crohn disease. J Pediatr Gastroenterol Nutr 54:769-75|
|Perito, Emily R; Mileti, Elizabeth; Dalal, Deepal H et al. (2012) Solitary rectal ulcer syndrome in children and adolescents. J Pediatr Gastroenterol Nutr 54:266-70|
|Perito, Emily Rothbaum; Glidden, Dave; Roberts, John Paul et al. (2012) Overweight and obesity in pediatric liver transplant recipients: prevalence and predictors before and after transplant, United Network for Organ Sharing Data, 1987-2010. Pediatr Transplant 16:41-9|
|Mileti, Elizabeth; Rosenthal, Philip; Peters, Marion G (2012) Validation and modification of simplified diagnostic criteria for autoimmune hepatitis in children. Clin Gastroenterol Hepatol 10:417-21.e1-2|
|Rook, Michelle; Vargas, Juan; Caughey, Aaron et al. (2012) Fetal outcomes in pregnancies complicated by intrahepatic cholestasis of pregnancy in a Northern California cohort. PLoS One 7:e28343|
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